Literature DB >> 28932715

Hemophagocytic lymphohistiocytosis (HLH): Elusive diagnosis of disseminated Mycobacterium avium complex infection.

Eloy E Ordaya1, Sulieman Abu Jarir2, Robert Yoo3, Pranatharthi H Chandrasekar4.   

Abstract

INTRODUCTION: Hemophagocytic lymphohistiocytosis (HLH) is a clinical syndrome of hyperinflammation leading to an uncontrolled and ineffective immune response, associated with high mortality. CASE REPORT: A 26-year-old woman with acute lymphoblastic leukemia, 8 months in remission, was found to have HLH. Without any improvement, stem cell transplantation was considered. Then, Mycobacterium avium complex (MAC) infection was identified as cause of her HLH. With appropriate therapy for infection, HLH improved and transplantation was averted.
CONCLUSION: MAC should be included in the list of potential causes of HLH.

Entities:  

Keywords:  Hemophagocytic lymphohistiocytosis; atypical mycobacteria; pancytopenia; unexplained fever

Year:  2017        PMID： 28932715      PMCID： PMC5601098          DOI： 10.18683/germs.2017.1120

Source DB:  PubMed          Journal:  Germs        ISSN： 2248-2997


  13 in total

1.  HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis.

Authors:  Jan-Inge Henter; Annacarin Horne; Maurizio Aricó; R Maarten Egeler; Alexandra H Filipovich; Shinsaku Imashuku; Stephan Ladisch; Ken McClain; David Webb; Jacek Winiarski; Gritta Janka
Journal:  Pediatr Blood Cancer       Date:  2007-02       Impact factor: 3.167

2.  Haemophagocytic lymphohistiocytosis associated with Mycobacterium tuberculosis infection.

Authors:  Yee Man Tracy Hui; Toby Pillinger; Asad Luqmani; Nichola Cooper
Journal:  BMJ Case Rep       Date:  2015-04-13

Review 3.  Hemophagocytic lymphohistiocytosis: Pathogenesis, diagnosis, and management.

Authors:  Akira Morimoto; Yozo Nakazawa; Eiichi Ishii
Journal:  Pediatr Int       Date:  2016-09       Impact factor: 1.524

4.  The role of infections in primary hemophagocytic lymphohistiocytosis: a case series and review of the literature.

Authors:  L Sung; S S Weitzman; M Petric; S M King
Journal:  Clin Infect Dis       Date:  2001-10-05       Impact factor: 9.079

Review 5.  Review of haemophagocytic lymphohistiocytosis.

Authors:  H R Freeman; A V Ramanan
Journal:  Arch Dis Child       Date:  2010-06-28       Impact factor: 3.791

Review 6.  Hemophagocytic lymphohistiocytosis in adults: diagnosis and treatment.

Authors:  Claire Larroche
Journal:  Joint Bone Spine       Date:  2012-03-29       Impact factor: 4.929

7.  Causes, clinical symptoms, and outcomes of infectious diseases associated with hemophagocytic lymphohistiocytosis in Taiwanese adults.

Authors:  Yu-Tzu Tseng; Wang-Huei Sheng; Bo-Han Lin; Chung-Wu Lin; Jann-Tay Wang; Yee-Chun Chen; Shan-Chwen Chang
Journal:  J Microbiol Immunol Infect       Date:  2011-01-20       Impact factor: 4.399

8.  Characteristics of pulmonary Mycobacterium avium complex disease diagnosed later in follow-up after negative mycobacterial study including bronchoscopy.

Authors:  Kazuya Koyama; Nobuharu Ohshima; Masahiro Kawashima; Kenichi Okuda; Ryota Sato; Hideaki Nagai; Hirotoshi Matsui; Ken Ohta
Journal:  Respir Med       Date:  2015-08-30       Impact factor: 3.415

9.  Disseminated Mycobacterium kansasii infection associated with hemophagocytic syndrome.

Authors:  Yu-Hsiang Chou; Meng-Shiuan Hsu; Wang-Huei Sheng; Shan-Chwen Chang
Journal:  Int J Infect Dis       Date:  2009-08-04       Impact factor: 3.623

10.  Disseminated tuberculosis presenting with secondary haemophagocytic lymphohistiocytosis and Poncet's disease in an immunocompetent individual.

Authors:  Kushal Naha; Sowjanya Dasari; G Vivek; Mukhyaprana Prabhu
Journal:  BMJ Case Rep       Date:  2013-04-05
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  1 in total

1.  Nontuberculous Mycobacterium infection complicated with Haemophagocytic syndrome: a case report and literature review.

Authors:  Wen Shi; Yang Jiao
Journal:  BMC Infect Dis       Date:  2019-05-09       Impact factor: 3.090
  1 in total

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