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Literature DB >> 28932532

Evacetrapib and cardiovascular outcomes: reasons for lack of efficacy.

Theodosios D Filippatos¹, Moses S Elisaf¹.

Abstract

Entities: Chemical

Year: 2017 PMID： 28932532 PMCID： PMC5594181 DOI： 10.21037/jtd.2017.07.75

Source DB: PubMed Journal: J Thorac Dis ISSN： 2072-1439 Impact factor: 2.895

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20 in total

1. Anacetrapib, but not evacetrapib, impairs endothelial function in CETP-transgenic mice in spite of marked HDL-C increase.

Authors: Branko Simic; Pavani Mocharla; Margot Crucet; Elena Osto; Adelheid Kratzer; Simona Stivala; Susan Kühnast; Thimoteus Speer; Petia Doycheva; Hans M Princen; Jose W van der Hoorn; J Wouter Jukema; Hector Giral; Anne Tailleux; Ulf Landmesser; Bart Staels; Thomas F Lüscher
Journal: Atherosclerosis Date: 2017-01-16 Impact factor: 5.162

2. Apolipoprotein C-III Levels and Incident Coronary Artery Disease Risk: The EPIC-Norfolk Prospective Population Study.

Authors: Julian C van Capelleveen; Sophie J Bernelot Moens; Xiaohong Yang; John J P Kastelein; Nicholas J Wareham; Aeilko H Zwinderman; Erik S G Stroes; Joseph L Witztum; G Kees Hovingh; Kay-Tee Khaw; S Matthijs Boekholdt; Sotirios Tsimikas
Journal: Arterioscler Thromb Vasc Biol Date: 2017-05-04 Impact factor: 8.311

3. Efficacy, safety, tolerability, and pharmacokinetic profile of evacetrapib administered as monotherapy or in combination with atorvastatin in Japanese patients with dyslipidemia.

Authors: Tamio Teramoto; Masakazu Takeuchi; Yoji Morisaki; Giacomo Ruotolo; Kathryn A Krueger
Journal: Am J Cardiol Date: 2014-04-02 Impact factor: 2.778

Review 4. Cholesteryl ester transfer protein inhibitors: challenges and perspectives.

Authors: T D Filippatos; E Klouras; F Barkas; M Elisaf
Journal: Expert Rev Cardiovasc Ther Date: 2016-05-28

5. Evacetrapib and Cardiovascular Outcomes in High-Risk Vascular Disease.

Authors: A Michael Lincoff; Stephen J Nicholls; Jeffrey S Riesmeyer; Philip J Barter; H Bryan Brewer; Keith A A Fox; C Michael Gibson; Christopher Granger; Venu Menon; Gilles Montalescot; Daniel Rader; Alan R Tall; Ellen McErlean; Kathy Wolski; Giacomo Ruotolo; Burkhard Vangerow; Govinda Weerakkody; Shaun G Goodman; Diego Conde; Darren K McGuire; Jose C Nicolau; Jose L Leiva-Pons; Yves Pesant; Weimin Li; David Kandath; Simon Kouz; Naeem Tahirkheli; Denise Mason; Steven E Nissen
Journal: N Engl J Med Date: 2017-05-18 Impact factor: 91.245

6. Effects of torcetrapib in patients at high risk for coronary events.

Authors: Philip J Barter; Mark Caulfield; Mats Eriksson; Scott M Grundy; John J P Kastelein; Michel Komajda; Jose Lopez-Sendon; Lori Mosca; Jean-Claude Tardif; David D Waters; Charles L Shear; James H Revkin; Kevin A Buhr; Marian R Fisher; Alan R Tall; Bryan Brewer
Journal: N Engl J Med Date: 2007-11-05 Impact factor: 91.245

7. Effects of dalcetrapib in patients with a recent acute coronary syndrome.

Authors: Gregory G Schwartz; Anders G Olsson; Markus Abt; Christie M Ballantyne; Philip J Barter; Jochen Brumm; Bernard R Chaitman; Ingar M Holme; David Kallend; Lawrence A Leiter; Eran Leitersdorf; John J V McMurray; Hardi Mundl; Stephen J Nicholls; Prediman K Shah; Jean-Claude Tardif; R Scott Wright
Journal: N Engl J Med Date: 2012-11-05 Impact factor: 91.245

8. Cholesterol Efflux Capacity and Pre-Beta-1 HDL Concentrations Are Increased in Dyslipidemic Patients Treated With Evacetrapib.

Authors: Stephen J Nicholls; Giacomo Ruotolo; H Bryan Brewer; John P Kane; Ming-Dauh Wang; Kathryn A Krueger; Steven J Adelman; Steven E Nissen; Daniel J Rader
Journal: J Am Coll Cardiol Date: 2015-11-17 Impact factor: 24.094