Literature DB >> 28929786

Eight new cucurbitane triterpenoids from "Xue Dan," the roots of Hemsleya pengxianensis.

Ying Li1,2,3, Wen-Xue Wang4, Zhong-Fei Zheng1,2,3, Yan-Ling Mu1,2,3, Yong-Jun Liu1,2,3, Hai-Yang Wang1,2,3, Ling Li1,4,2,3, Qing-Qiang Yao1,4,2,3.   

Abstract

Eight new natural products (four new cucurbitane aglycones, hemslepencins A-D (1-4), four new cucurbitane glucosides, hemslepensides F-I (5-8), along with seven known compounds (9-15), were isolated from the roots of Hemsleya pengxianensis. The structures of 1-8 were elucidated using IR, HRESIMS, and NMR. Compound 3 exhibited cytotoxic activity against the human cancer cell lines.

Entities:  

Keywords:  Cucurbitaceae; Hemsleya pengxianensis; cucurbitane triterpenoid; cytotoxic activity

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Year:  2017        PMID: 28929786     DOI: 10.1080/10286020.2017.1355363

Source DB:  PubMed          Journal:  J Asian Nat Prod Res        ISSN: 1028-6020            Impact factor:   1.569


  3 in total

1.  Five New Cucurbitane-Type Triterpenoid Glycosides from the Rhizomes of Hemsleya penxianensis with Cytotoxic Activities.

Authors:  De-Li Chen; Xu-Dong Xu; Rong-Tao Li; Bo-Wen Wang; Meng Yu; Yang-Yang Liu; Guo-Xu Ma
Journal:  Molecules       Date:  2019-08-13       Impact factor: 4.411

2.  Synthesis of cucurbitacin IIa derivatives with apoptosis-inducing capabilities in human cancer cells.

Authors:  Kun Yu; Xinmei Yang; Ying Li; Xue Cui; Bo Liu; Qingqiang Yao
Journal:  RSC Adv       Date:  2020-01-23       Impact factor: 4.036

3.  Identification of 16,25-O-diacetyl-cucurbitane F and 25-O-acetyl-23,24-dihydrocucurbitacin F as novel anti-cancer chemicals.

Authors:  Wenxue Wang; Haoran Yang; Ying Li; Zhongfei Zheng; Yongjun Liu; Haiyang Wang; Yanling Mu; Qingqiang Yao
Journal:  R Soc Open Sci       Date:  2018-08-15       Impact factor: 2.963

  3 in total

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