Literature DB >> 28929550

Characteristics and clinical outcomes of pleomorphic lobular carcinoma in situ of the breast.

Carolina E Fasola1, Jie Jane Chen1, Kristin C Jensen2,3, Kimberly H Allison2, Kathleen C Horst1.   

Abstract

Pleomorphic lobular carcinoma in situ (PLCIS) of the breast is a rare variant of lobular carcinoma in situ (LCIS). We reviewed 78 cases of PLCIS diagnosed at our institution from 1998 to 2012. Among all cases, 47 (60%) were associated with invasive carcinoma and/or ductal carcinoma in situ (DCIS) after final surgical excision. Of the 20 cases with PLCIS alone on core needle biopsy (CNB), 6 (30%) were upgraded to invasive carcinoma or DCIS after final surgical excision. Our findings support a recommendation for complete surgical excision of PLCIS when diagnosed on CNB.
© 2017 Wiley Periodicals, Inc.

Entities:  

Keywords:  breast disease; pleomorphic lobular carcinoma in situ; surgical margins

Mesh：

Year:  2017        PMID： 28929550     DOI： 10.1111/tbj.12843

Source DB:  PubMed          Journal:  Breast J        ISSN： 1075-122X            Impact factor:   2.431


  7 in total

Review 1.  American Registry of Pathology Expert Opinions: The Spectrum of Lobular Carcinoma in Situ: Diagnostic Features and Clinical Implications.

Authors:  Stuart J Schnitt; Edi Brogi; Yunn-Yi Chen; Tari A King; Sunil R Lakhani
Journal:  Ann Diagn Pathol       Date:  2020-02-15       Impact factor: 2.090

Review 2.  The morphologic spectrum of lobular carcinoma in situ (LCIS) observations on clinical significance, management implications and diagnostic pitfalls of classic, florid and pleomorphic LCIS.

Authors:  Edi Brogi
Journal:  Virchows Arch       Date:  2022-05-14       Impact factor: 4.064

Review 3.  Lobular carcinoma in situ: diagnostic criteria and molecular correlates.

Authors:  Anna Sokolova; Sunil R Lakhani
Journal:  Mod Pathol       Date:  2020-10-06       Impact factor: 7.842

4.  Genetic analysis of pleomorphic and florid lobular carcinoma in situ variants: frequent ERBB2/ERBB3 alterations and clonal relationship to classic lobular carcinoma in situ and invasive lobular carcinoma.

Authors:  Eliah R Shamir; Yunn-Yi Chen; Gregor Krings
Journal:  Mod Pathol       Date:  2020-01-06       Impact factor: 7.842

5.  Morphologic subtypes of lobular carcinoma in situ diagnosed on core needle biopsy: clinicopathologic features and findings at follow-up excision.

Authors:  M Gabriela Kuba; Melissa P Murray; Kristen Coffey; Catarina Calle; Monica Morrow; Edi Brogi
Journal:  Mod Pathol       Date:  2021-04-06       Impact factor: 7.842

Review 6.  High-risk lesions of the breast: concurrent diagnostic tools and management recommendations.

Authors:  Francesca Catanzariti; Daly Avendano; Giuseppe Cicero; Margarita Garza-Montemayor; Carmelo Sofia; Emmanuele Venanzi Rullo; Giorgio Ascenti; Katja Pinker-Domenig; Maria Adele Marino
Journal:  Insights Imaging       Date:  2021-05-26

Review 7.  Second International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions).

Authors:  Christoph J Rageth; Elizabeth A M O'Flynn; Katja Pinker; Rahel A Kubik-Huch; Alexander Mundinger; Thomas Decker; Christoph Tausch; Florian Dammann; Pascal A Baltzer; Eva Maria Fallenberg; Maria P Foschini; Sophie Dellas; Michael Knauer; Caroline Malhaire; Martin Sonnenschein; Andreas Boos; Elisabeth Morris; Zsuzsanna Varga
Journal:  Breast Cancer Res Treat       Date:  2018-11-30       Impact factor: 4.872
  7 in total

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