C J Alvarez-Laso1, S Moral2, D Rodríguez3, A Carrocera2, E Azcano2, A Cabrera2, R Rodríguez2. 1. Colorectal Unit, Surgery Department, Hospital Universitario de Cabueñes, Gijón, Spain. alvarezlaso@hotmail.com. 2. Colorectal Unit, Surgery Department, Hospital Universitario de Cabueñes, Gijón, Spain. 3. Pathology Department, Hospital Universitario de Cabueñes, Gijón, Spain.
Abstract
INTRODUCTION: Mucinous adenocarcinoma on perianal fistula is a rare entity; it could be underdiagnosed because it behaves often as a regular perianal fistula. MATERIALS AND METHODS: We have recently treated four cases in our unit. We present them and review the literature, emphasizing on clinical characteristic and therapeutic options. The four patients were male with a mean age of 64. Three of them were classified as locally advances cases and therefore treated with neoadjuvant therapy. RESULTS: All of them underwent laparoscopic abdominoperineal escisión. Surgical specimens are described and clinical characteristic specified. Review of the literature shows that this disease has a very high potential risk of local recurrence and we must be aggressive with the resection. Sometimes plastic surgery is needed to reconstruct the perianal wound. CONCLUSIONS: Mucinous adenocarcinoma associated with anal fistula is a rare disease. Neoadjuvant chemoradiotherapy followed by an adequate abdominoperineal excision may result in favourable outcomes.
INTRODUCTION:Mucinous adenocarcinoma on perianal fistula is a rare entity; it could be underdiagnosed because it behaves often as a regular perianal fistula. MATERIALS AND METHODS: We have recently treated four cases in our unit. We present them and review the literature, emphasizing on clinical characteristic and therapeutic options. The four patients were male with a mean age of 64. Three of them were classified as locally advances cases and therefore treated with neoadjuvant therapy. RESULTS: All of them underwent laparoscopic abdominoperineal escisión. Surgical specimens are described and clinical characteristic specified. Review of the literature shows that this disease has a very high potential risk of local recurrence and we must be aggressive with the resection. Sometimes plastic surgery is needed to reconstruct the perianal wound. CONCLUSIONS:Mucinous adenocarcinoma associated with anal fistula is a rare disease. Neoadjuvant chemoradiotherapy followed by an adequate abdominoperineal excision may result in favourable outcomes.
Authors: Wolfgang B Gaertner; Gonzalo F Hagerman; Charles O Finne; Karim Alavi; Jose Jessurun; David A Rothenberger; Robert D Madoff Journal: Dis Colon Rectum Date: 2008-04-17 Impact factor: 4.585
Authors: Ana Beatriz Pereira de Souza; Amanda Pereira Lima; Lívia Moreira Genaro; Carla Peres Fingerhut Geiger; Maria de Lourdes Setsuko Ayrizono; Raquel Franco Leal Journal: Int J Surg Case Rep Date: 2022-05-18