| Literature DB >> 28929189 |
W Fenske1.
Abstract
Hyponatremia is the most common electrolyte disorder in clinical practice and associated with increased morbidity and mortality, independent of underlying disease. Untreated acute hyponatremia can cause substantial morbidity and mortality as a result of osmotically induced cerebral edema whilst over rapid correction of chronic hyponatremia can cause serious neurologic impairment and death resulting from osmotic demyelination. Still hyponatremia is often neglected and insufficiently addressed, most likely due to limited understanding of its pathophysiological mechanisms. Being familiar with only few basic principles of body fluid regulation may be a worthwhile investment into the clinical career and save patients' lives.Entities:
Keywords: Guidelines; Neurologic manifestations; Saline solution, hypertonic; Syndrome of inappropriate ADH (SIADH) secretion; Tolvaptan
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Year: 2017 PMID: 28929189 DOI: 10.1007/s00108-017-0315-z
Source DB: PubMed Journal: Internist (Berl) ISSN: 0020-9554 Impact factor: 0.743