Literature DB >> 2892891

Induction of glutamine synthetase in rat astrocytes by co-cultivation with embryonic chick neurons.

D K Wu1, S Scully, J de Vellis.   

Abstract

Co-cultivation of confluent rat astrocyte cultures with embryonic chick neurons resulted in induction of glutamine synthetase activity in the astrocytes. This induction of glutamine synthetase in astrocytes by neurons was independent of induction by hydrocortisone and forskolin, but was dependent on the length of co-cultivation and the number of neurons present in the co-culture. Cycloheximide and actinomycin D inhibited the induction of glutamine synthetase in astrocytes by neurons, whereas cytosine arabinoside had no apparent effect. Results suggest that this induction of glutamine synthetase in astrocytes is mediated by cell contact with neurons and may represent a specific neuronal and glial interaction.

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Year:  1988        PMID： 2892891     DOI： 10.1111/j.1471-4159.1988.tb03001.x

Source DB:  PubMed          Journal:  J Neurochem        ISSN： 0022-3042            Impact factor:   5.372


  7 in total

1.  Demonstration of neuron-glia transfer of precursors for GABA biosynthesis in a co-culture system of dissociated mouse cerebral cortex.

Authors:  Renata Leke; Lasse K Bak; Arne Schousboe; Helle S Waagepetersen
Journal:  Neurochem Res       Date:  2008-08-16       Impact factor: 3.996

2.  Neuronal modulation of calcium channel activity in cultured rat astrocytes.

Authors:  V Corvalan; R Cole; J de Vellis; S Hagiwara
Journal:  Proc Natl Acad Sci U S A       Date:  1990-06       Impact factor: 11.205

3.  Early and late passage C-6 glial cell growth: similarities with primary glial cells in culture.

Authors:  D Mangoura; N Sakellaridis; J Jones; A Vernadakis
Journal:  Neurochem Res       Date:  1989-10       Impact factor: 3.996

4.  Glucocorticoid receptor pathways are involved in the inhibition of astrocyte proliferation.

Authors:  K L Crossin; M H Tai; L A Krushel; V P Mauro; G M Edelman
Journal:  Proc Natl Acad Sci U S A       Date:  1997-03-18       Impact factor: 11.205

5.  Involvement of a C/EBP-like protein in the acquisition of responsiveness to glucocorticoid hormones during chick neural retina development.

Authors:  S Ben-Or; S Okret
Journal:  Mol Cell Biol       Date:  1993-01       Impact factor: 4.272

6.  Effect of fructose-1,6-bisphosphate on glutamate uptake and glutamine synthetase activity in hypoxic astrocyte cultures.

Authors:  J A Kelleher; G A Gregory; P H Chan
Journal:  Neurochem Res       Date:  1994-02       Impact factor: 3.996

7.  Acute Liver Toxicity Modifies Protein Expression of Glutamate Transporters in Liver and Cerebellar Tissue.

Authors:  Catya Jiménez-Torres; Hoda El-Kehdy; Luisa C Hernández-Kelly; Etienne Sokal; Arturo Ortega; Mustapha Najimi
Journal:  Front Neurosci       Date:  2021-01-06       Impact factor: 4.677
  7 in total

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