biospear: an R package for biomarker selection in penalized Cox regression.

Summary: The R package biospear allows selecting the biomarkers with the strongest impact on survival and on the treatment effect in high-dimensional Cox models, and estimating expected survival probabilities. Most of the implemented approaches are based on penalized regression techniques. Availability and implementation: The package is available on the CRAN. (https://CRAN.R-project.org/package=biospear). Contact: stefan.michiels@gustaveroussy.fr. Supplementary information: Supplementary data are available at Bioinformatics online.