Literature DB >> 28927134

Primary mucinous adenocarcinoma of the lung: A case report and review of the literature.

Yan Liu1,2, He-Long Zhang3, Jia-Zhuan Mei1, Yan-Wei Guo1, Rui-Jun Li1, Si-Dong Wei2, Fu Tian2, Lu Yang2, Hui Wang2.   

Abstract

Mucinous adenocarcinoma is an unusual histological type of lung cancer, and its clinicopathological feature is distinctive from that of other histopathological types of lung adenocarcinoma. Mucinous adenocarcinoma has a mucus-producing function, which explains its name. The present study reports a rare case of a mucus-producing adenocarcinoma of the lung. A 60-year-old Chinese female patient was diagnosed with mucinous adenocarcinoma of the lung, which manifested as respiratory symptoms, including fever, cough and expectoration. The patient received thoracic exploratory operation and right pneumonectomy, since the above respiratory symptoms seriously affected her daily life, and other inspections could not establish the diagnosis. Histopathology revealed no mutations in epidermal growth factor receptor. The patient received adjuvant chemotherapy using taxol and cisplatin. However, metastases in the left lung were detected 7 months after the operation. Pemetrexed and cisplatin were used as the second-line treatment. The patient survived 3 years after the initial diagnosis. The present study reports a rare mucus-producing adenocarcinoma of the lung, which is of bad prognosis. Therefore, further studies on this type of cancer are urgently required.

Entities:  

Keywords:  CT scan; lung mucinous adenocarcinoma

Year:  2017        PMID: 28927134      PMCID: PMC5587939          DOI: 10.3892/ol.2017.6615

Source DB:  PubMed          Journal:  Oncol Lett        ISSN: 1792-1074            Impact factor:   2.967


  13 in total

1.  Correlation of EGFR mutation and histological subtype according to the IASLC/ATS/ERS classification of lung adenocarcinoma.

Authors:  Zhen Chen; Xiaoyan Liu; Jing Zhao; Hanjin Yang; Xiaodong Teng
Journal:  Int J Clin Exp Pathol       Date:  2014-10-15

2.  Bronchioloalveolar lung carcinomas: K-ras mutations are constant events in the mucinous subtype.

Authors:  A Marchetti; F Buttitta; S Pellegrini; A Chella; G Bertacca; A Filardo; V Tognoni; F Ferreli; E Signorini; C A Angeletti; G Bevilacqua
Journal:  J Pathol       Date:  1996-07       Impact factor: 7.996

3.  Calcineurin promotes proliferation, migration, and invasion of small cell lung cancer.

Authors:  Yan Liu; Ye Zhang; Jie Min; Li-Li Liu; Ning-Qiang Ma; Ying-Ming Feng; Dong Liu; Ping-zhong Wang; De-Dong Huang; Yan Zhuang; He-Long Zhang
Journal:  Tumour Biol       Date:  2010-04-27

4.  The effect of down regulation of calcineurin Aα by lentiviral vector-mediated RNAi on the biological behavior of small-cell lung cancer and its bone metastasis.

Authors:  Ning-Qiang Ma; Li-Li Liu; Jie Min; Jun-Wei Wang; Wei-Feng Jiang; Yan Liu; Yan-Guo Feng; Hai-Chuan Su; Ying-Ming Feng; He-Long Zhang
Journal:  Clin Exp Metastasis       Date:  2011-07-23       Impact factor: 5.150

5.  The IASLC lung cancer staging project: a proposal for a new international lymph node map in the forthcoming seventh edition of the TNM classification for lung cancer.

Authors:  Valerie W Rusch; Hisao Asamura; Hirokazu Watanabe; Dorothy J Giroux; Ramon Rami-Porta; Peter Goldstraw
Journal:  J Thorac Oncol       Date:  2009-05       Impact factor: 15.609

Review 6.  New pathologic classification of lung cancer: relevance for clinical practice and clinical trials.

Authors:  William D Travis; Elisabeth Brambilla; Gregory J Riely
Journal:  J Clin Oncol       Date:  2013-02-11       Impact factor: 44.544

7.  Druggable oncogene fusions in invasive mucinous lung adenocarcinoma.

Authors:  Takashi Nakaoku; Koji Tsuta; Hitoshi Ichikawa; Kouya Shiraishi; Hiromi Sakamoto; Masato Enari; Koh Furuta; Yoko Shimada; Hideaki Ogiwara; Shun-ichi Watanabe; Hiroshi Nokihara; Kazuki Yasuda; Masaki Hiramoto; Takao Nammo; Teruhide Ishigame; Aaron J Schetter; Hirokazu Okayama; Curtis C Harris; Young Hak Kim; Michiaki Mishima; Jun Yokota; Teruhiko Yoshida; Takashi Kohno
Journal:  Clin Cancer Res       Date:  2014-04-11       Impact factor: 12.531

8.  Cystic mucinous adenocarcinoma of the lung. Two cases of cystic variant of mucus-producing lung adenocarcinoma.

Authors:  M Higashiyama; O Doi; K Kodama; H Yokouchi; R Tateishi
Journal:  Chest       Date:  1992-03       Impact factor: 9.410

Review 9.  The IASLC Lung Cancer Staging Project: data elements for the prospective project.

Authors:  Dorothy J Giroux; Ramón Rami-Porta; Kari Chansky; John J Crowley; Patti A Groome; Pieter E Postmus; Valerie Rusch; Jean-Paul Sculier; Frances A Shepherd; Leslie Sobin; Peter Goldstraw
Journal:  J Thorac Oncol       Date:  2009-06       Impact factor: 15.609

10.  Comparison of clinical features, molecular alterations, and prognosis in morphological subgroups of lung invasive mucinous adenocarcinoma.

Authors:  Deng Cai; Hang Li; Rui Wang; Yuan Li; Yunjian Pan; Haichuan Hu; Yang Zhang; Ranxia Gong; Bin Pan; Yihua Sun; Haiquan Chen
Journal:  Onco Targets Ther       Date:  2014-11-18       Impact factor: 4.147

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  2 in total

1.  Effect of invasive mucinous adenocarcinoma on lung cancer-specific survival after surgical resection: a population-based study.

Authors:  Seok Whan Moon; Si Young Choi; Mi Hyoung Moon
Journal:  J Thorac Dis       Date:  2018-06       Impact factor: 2.895

2.  Analysis of the clinicopathological characteristics, genetic phenotypes, and prognostic of pure mucinous adenocarcinoma.

Authors:  Zhencong Chen; Ming Li; Ke Ma; Guoguo Shang; Jiaqi Liang; Jiacheng Yin; Jizhuang Luo; Cheng Zhan; Yu Shi; Qun Wang
Journal:  Cancer Med       Date:  2019-11-25       Impact factor: 4.452

  2 in total

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