OBJECTIVES: To compare individuals with mild and moderate/severe traumatic brain injury (TBI) on alcohol and drug use and substance use disorders before and in the first year post-TBI; to explore sociodemographic and injury-related variables associated with substance use disorders. PARTICIPANTS: A total of 225 adults hospitalized in a level I trauma center after TBI. DESIGN: Observational cohort study with retrospective (pre-TBI) and prospective (4, 8, and 12 months post-TBI) assessments. MAIN MEASURES: Mini International Neuropsychiatric Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). RESULTS: The percentage of participants using alcohol or drug declined shortly after the injury (4 months) but increased closer to preinjury levels by the end of the first year. Post-TBI alcohol use was higher after mild than moderate/severe TBI, but drug use was similar. About 11% of participants met criteria for a substance use disorder in the first year after TBI. Younger age, not being in a relationship, and suspected substance intoxication at the time of TBI were associated with the presence of a post-TBI substance use disorder. CONCLUSION: Individuals with milder injuries return to alcohol use earlier than those with more severe injuries. Given that substance use may alter recovery, preventive recommendations and systematic follow-ups are warranted regardless of injury severity and access to rehabilitation.
OBJECTIVES: To compare individuals with mild and moderate/severe traumatic brain injury (TBI) on alcohol and drug use and substance use disorders before and in the first year post-TBI; to explore sociodemographic and injury-related variables associated with substance use disorders. PARTICIPANTS: A total of 225 adults hospitalized in a level I trauma center after TBI. DESIGN: Observational cohort study with retrospective (pre-TBI) and prospective (4, 8, and 12 months post-TBI) assessments. MAIN MEASURES: Mini International Neuropsychiatric Interview for Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). RESULTS: The percentage of participants using alcohol or drug declined shortly after the injury (4 months) but increased closer to preinjury levels by the end of the first year. Post-TBI alcohol use was higher after mild than moderate/severe TBI, but drug use was similar. About 11% of participants met criteria for a substance use disorder in the first year after TBI. Younger age, not being in a relationship, and suspected substance intoxication at the time of TBI were associated with the presence of a post-TBI substance use disorder. CONCLUSION: Individuals with milder injuries return to alcohol use earlier than those with more severe injuries. Given that substance use may alter recovery, preventive recommendations and systematic follow-ups are warranted regardless of injury severity and access to rehabilitation.
Authors: Lee Anne Cannella; Allison M Andrews; Roshanak Razmpour; Hannah McGary; Cali B Corbett; Jana Kahn; Servio H Ramirez Journal: Behav Brain Res Date: 2019-11-01 Impact factor: 3.332
Authors: Flora M Hammond; Jessica Ketchum; Kristen Dams-O'Connor; John D Corrigan; Cate Miller; Juliet Haarbauer-Krupa; Mark Faul; Lance E Trexler; Cynthia Harrison-Felix Journal: J Neurotrauma Date: 2020-07-08 Impact factor: 5.269
Authors: Rachel Sayko Adams; Jessica M Ketchum; Risa Nakase-Richardson; Douglas I Katz; John D Corrigan Journal: Am J Phys Med Rehabil Date: 2021-08-01 Impact factor: 3.412
Authors: Raj G Kumar; Katherine A Ornstein; John D Corrigan; Rachel Sayko Adams; Kristen Dams-O'Connor Journal: J Neurotrauma Date: 2021-03-11 Impact factor: 4.869
Authors: Zachary F Stielper; Elizabeth A Fucich; Jason W Middleton; Cecilia J Hillard; Scott Edwards; Patricia E Molina; Nicholas W Gilpin Journal: J Neurotrauma Date: 2020-09-30 Impact factor: 4.869
Authors: Son T Ton; Natalie S Adamczyk; Jack P Gerling; Ian C Vaagenes; Joanna Y Wu; Kevin Hsu; Timothy E O'Brien; Shih-Yen Tsai; Gwendolyn L Kartje Journal: Neurosci Insights Date: 2020-11-10