| Literature DB >> 28925255 |
Christopher D McNitt, Hazel Cheng1, Susanne Ullrich, Vladimir V Popik, Matthew Bjerknes1.
Abstract
Irradiation of cyclopropenone-masked dibenzocyclooctynes with near-infrared pulses from a femtosecond laser triggers photodecarbonylation via nonresonant two- or three-photon excitation. Multiphoton-generated cyclooctynes undergo a SPAAC reaction with organic azides, yielding the expected triazoles. Multiphoton-triggered SPAAC (MP-SPAAC) enables high resolution 3-D photoclick derivatization of hydrogels and tissues.Entities:
Year: 2017 PMID: 28925255 DOI: 10.1021/jacs.7b08472
Source DB: PubMed Journal: J Am Chem Soc ISSN: 0002-7863 Impact factor: 15.419