| Literature DB >> 28924672 |
Brian J Beliveau1,2,3, Alistair N Boettiger4,5,6, Guy Nir1, Bogdan Bintu4,7, Peng Yin8,9, Xiaowei Zhuang10,11,12, C-Ting Wu13.
Abstract
OligoSTORM and OligoDNA-PAINT meld the Oligopaint technology for fluorescent in situ hybridization (FISH) with, respectively, Stochastic Optical Reconstruction Microscopy (STORM) and DNA-based Point Accumulation for Imaging in Nanoscale Topography (DNA-PAINT) to enable in situ single-molecule super-resolution imaging of nucleic acids. Both strategies enable ≤20 nm resolution and are appropriate for imaging nanoscale features of the genomes of a wide range of species, including human, mouse, and fruit fly (Drosophila).Entities:
Keywords: Chromatin; Chromosomes; DNA-PAINT; FISH; Genome; OligoDNA-PAINT; OligoSTORM; Oligopaint; STORM; Single-molecule; Super-resolution
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Year: 2017 PMID： 28924672 PMCID： PMC5919218 DOI： 10.1007/978-1-4939-7265-4_19
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745