Literature DB >> 28923565

Chitin and chitosan preparation from shrimp shells Penaeus monodon and its human ovarian cancer cell line, PA-1.

Haripriya Srinivasan1, Velayutham Kanayairam1, Ramanibai Ravichandran2.   

Abstract

In the present study, chitin and chitosan preparation from shrimp shells Penaeus mondon and its ovarian cancer cell line (PA-1). FTIR spectrum sharp absorption peak at 1655cm-1 is assigned to ketone C=O (α) unsaturated with chitosan. X-ray diffraction showed the presence of chitin and chitosan were strongest peak at 18.91° (β) and 29.75° (α) characters. SEM observations of chitin and chitosan surface morphologies of P. monodon showed that microfibril and porous structures. Anticancer activity of chitin and chitosan against human ovarian cancer cell line showed that chitosan an exhibited notable higher activity than chitin. Anticancer activity of aquacultural waste of shrimp shells mediated chitosan, which was proved to be good novel pharmaceutical industries.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Chitin; Chitosan; FTIR; Penaeus monodon

Mesh:

Substances:

Year:  2017        PMID: 28923565     DOI: 10.1016/j.ijbiomac.2017.09.035

Source DB:  PubMed          Journal:  Int J Biol Macromol        ISSN: 0141-8130            Impact factor:   6.953


  14 in total

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