Sze Man Tse1, Christian Samson2. 1. Division of Respiratory Medicine, Department of Pediatrics, Sainte-Justine University Hospital Center and University of Montreal, Montreal, QC, Canada. 2. Department of Statistics, University of British Columbia, Vancouver, BC, Canada.
Abstract
OBJECTIVES: To compare the time to asthma-related readmissions between children with a previous ICU hospitalization for asthma and those with a non-ICU hospitalization and to explore predictors of time to readmission in children admitted to the ICU. DESIGN: Retrospective cohort study using a pan-Canadian administrative inpatient database from April 1, 2008, to March 31, 2014. SETTING: All adult and pediatric Canadian hospitals. SUBJECTS: Children 2-17 years old with a hospitalization for asthma. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: A total of 26,168 children were hospitalized 33,304 times during the study period. The time to readmission was shorter in the ICU group compared with the non-ICU group (median time to readmission 27 mo in ICU vs 35 mo in non-ICU group). Preschool-aged children (hazard ratio, 1.48; 95% CI, 1.02-2.14) and increased length of stay (hazard ratio, 1.63; 95% CI, 1.17-2.27) were associated with a shorter time to readmission. CONCLUSIONS: Children previously admitted to the ICU for asthma had a shorter time to asthma-related readmission, compared with children who did not require intensive care, underlining the importance of targeted long-term postdischarge follow-up of these children. Children of preschool age and who have a lengthier hospital stay are particularly at risk for future morbidity.
OBJECTIVES: To compare the time to asthma-related readmissions between children with a previous ICU hospitalization for asthma and those with a non-ICU hospitalization and to explore predictors of time to readmission in children admitted to the ICU. DESIGN: Retrospective cohort study using a pan-Canadian administrative inpatient database from April 1, 2008, to March 31, 2014. SETTING: All adult and pediatric Canadian hospitals. SUBJECTS:Children 2-17 years old with a hospitalization for asthma. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: A total of 26,168 children were hospitalized 33,304 times during the study period. The time to readmission was shorter in the ICU group compared with the non-ICU group (median time to readmission 27 mo in ICU vs 35 mo in non-ICU group). Preschool-aged children (hazard ratio, 1.48; 95% CI, 1.02-2.14) and increased length of stay (hazard ratio, 1.63; 95% CI, 1.17-2.27) were associated with a shorter time to readmission. CONCLUSIONS:Children previously admitted to the ICU for asthma had a shorter time to asthma-related readmission, compared with children who did not require intensive care, underlining the importance of targeted long-term postdischarge follow-up of these children. Children of preschool age and who have a lengthier hospital stay are particularly at risk for future morbidity.
Authors: Shelley A Boeschoten; Annemie L Boehmer; Peter J Merkus; Joost van Rosmalen; Johan C de Jongste; Pieter L A Fraaij; Richard Molenkamp; Sabien G Heisterkamp; Job B van Woensel; Berber Kapitein; Eric G Haarman; Roelie M Wösten-van Asperen; Martin C Kneyber; Joris Lemson; Stan Hartman; Dick A van Waardenburg; Heleen E Bunker-Wiersma; Carole N Brouwer; Bart E van Ewijk; Anneke M Landstra; Mariel Verwaal; Anja A Vaessen-Verberne; Sanne Hammer; Corinne M Buysse; Matthijs de Hoog Journal: ERJ Open Res Date: 2020-08-17