Literature DB >> 28921783

Barriers to listing for HIV-infected patients being evaluated for kidney transplantation.

Dong Heun Lee1, Suzanne M Boyle1, Gregory E Malat2, Christopher Kern1, Charles Milrod1, Shannon DeBellis1, Meera N Harhay1, Karthik Ranganna1, Stephen Guy2, Sindhura Talluri1, Tiffany Bias1, Alden Doyle1.   

Abstract

Human immunodeficiency virus (HIV)-infected patients have excellent outcomes following kidney transplantation (KT) but still might face barriers in the evaluation and listing process. The aim of this study was to characterize the patient population, referral patterns, and outcomes of HIV-infected patients who present for KT evaluation. We performed a single-center retrospective cohort study of HIV-infected patients who were evaluated for KT. The primary outcome was time to determination of eligibility for KT. Between 2011 and 2015, 105 HIV-infected patients were evaluated for KT. Of the 105 patients, 73 were listed for transplantation by the end of the study period. For those who were deemed ineligible, the most common reasons cited were active substance abuse (n = 7, 22%) and failure to complete the full transplant evaluation (n = 7, 22%). Our cohort demonstrated a higher proportion of HIV-infected patients eligible for KT than in previous studies, likely secondary to advances in HIV management. Among those who were denied access to transplantation, we identified that many were unable to complete the evaluation process, and that active substance abuse was common. Future prospective studies should examine reasons and potential interventions for the lack of follow-through and drug use we observed in this population.
© 2017 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.

Entities:  

Keywords:  HIV; barrier; evaluation; kidney transplantation

Mesh:

Substances:

Year:  2017        PMID: 28921783      PMCID: PMC5745286          DOI: 10.1111/tid.12777

Source DB:  PubMed          Journal:  Transpl Infect Dis        ISSN: 1398-2273            Impact factor:   2.228


  15 in total

1.  Trends in diseases reported on U.S. death certificates that mentioned HIV infection, 1987-1999.

Authors:  Richard M Selik; Robert H Byers; Mark S Dworkin
Journal:  J Acquir Immune Defic Syndr       Date:  2002-04-01       Impact factor: 3.731

2.  An Assessment of HIV-Infected Patients Dying in Care for Deceased Organ Donation in a United States Urban Center.

Authors:  A Richterman; D Sawinski; P P Reese; D H Lee; H Clauss; R D Hasz; A Thomasson; D S Goldberg; P L Abt; K A Forde; R D Bloom; S L Doll; K A Brady; E A Blumberg
Journal:  Am J Transplant       Date:  2015-05-14       Impact factor: 8.086

3.  Estimating the potential pool of HIV-infected deceased organ donors in the United States.

Authors:  B J Boyarsky; E C Hall; A L Singer; R A Montgomery; K A Gebo; D L Segev
Journal:  Am J Transplant       Date:  2011-03-28       Impact factor: 8.086

4.  Risk factors for ESRD in HIV-infected individuals: traditional and HIV-related factors.

Authors:  Vasantha Jotwani; Yongmei Li; Carl Grunfeld; Andy I Choi; Michael G Shlipak
Journal:  Am J Kidney Dis       Date:  2011-12-28       Impact factor: 8.860

5.  Clinical practice guideline for the management of chronic kidney disease in patients infected with HIV: 2014 update by the HIV Medicine Association of the Infectious Diseases Society of America.

Authors:  Gregory M Lucas; Michael J Ross; Peter G Stock; Michael G Shlipak; Christina M Wyatt; Samir K Gupta; Mohamed G Atta; Kara K Wools-Kaloustian; Paul A Pham; Leslie A Bruggeman; Jeffrey L Lennox; Patricio E Ray; Robert C Kalayjian
Journal:  Clin Infect Dis       Date:  2014-09-17       Impact factor: 9.079

6.  Safety and success of kidney transplantation and concomitant immunosuppression in HIV-positive patients.

Authors:  Mysore S Anil Kumar; Debra R Sierka; Anna M Damask; Billie Fyfe; Robert F McAlack; Michael Heifets; Michael J Moritz; Daniel Alvarez; Aparna Kumar
Journal:  Kidney Int       Date:  2005-04       Impact factor: 10.612

7.  Outcomes of kidney transplantation in HIV-infected recipients.

Authors:  Peter G Stock; Burc Barin; Barbara Murphy; Douglas Hanto; Jorge M Diego; Jimmy Light; Charles Davis; Emily Blumberg; David Simon; Aruna Subramanian; J Michael Millis; G Marshall Lyon; Kenneth Brayman; Doug Slakey; Ron Shapiro; Joseph Melancon; Jeffrey M Jacobson; Valentina Stosor; Jean L Olson; Donald M Stablein; Michelle E Roland
Journal:  N Engl J Med       Date:  2010-11-18       Impact factor: 91.245

8.  A National Study of Outcomes among HIV-Infected Kidney Transplant Recipients.

Authors:  Jayme E Locke; Shikha Mehta; Rhiannon D Reed; Paul MacLennan; Allan Massie; Anoma Nellore; Christine Durand; Dorry L Segev
Journal:  J Am Soc Nephrol       Date:  2015-03-19       Impact factor: 10.121

9.  Access to Kidney Transplantation among HIV-Infected Waitlist Candidates.

Authors:  Jayme E Locke; Shikha Mehta; Deirdre Sawinski; Sally Gustafson; Brittany A Shelton; Rhiannon D Reed; Paul MacLennan; Charlotte Bolch; Christine Durand; Allan Massie; Roslyn B Mannon; Robert Gaston; Michael Saag; Turner Overton; Dorry L Segev
Journal:  Clin J Am Soc Nephrol       Date:  2017-02-23       Impact factor: 8.237

10.  Center-Level Experience and Kidney Transplant Outcomes in HIV-Infected Recipients.

Authors:  J E Locke; R D Reed; S G Mehta; C Durand; R B Mannon; P MacLennan; B Shelton; M Y Martin; H Qu; R Shewchuk; D L Segev
Journal:  Am J Transplant       Date:  2015-03-13       Impact factor: 8.086

View more
  5 in total

1.  Disparity in access to kidney allograft offers among transplant candidates with human immunodeficiency virus.

Authors:  Jordana B Cohen; Jayme E Locke; Brittany Shelton; Rhiannon D Reed; Margaux Mustian; Paul MacLennan; Kimberly A Forde; Peter P Reese; Deirdre Sawinski
Journal:  Clin Transplant       Date:  2019-01-12       Impact factor: 2.863

2.  Kidney Transplantation in a HIV-Positive Recipient.

Authors:  Deirdre Sawinski; Jayme E Locke
Journal:  Clin J Am Soc Nephrol       Date:  2019-03-18       Impact factor: 8.237

3.  Barriers to kidney transplant evaluation in HIV-positive patients with advanced kidney disease: A single-center study.

Authors:  Suzanne M Boyle; Kallie Fehr; Catylin Deering; Abbas Raza; Meera N Harhay; Gregory Malat; Karthik Ranganna; Dong Heun Lee
Journal:  Transpl Infect Dis       Date:  2020-02-12       Impact factor: 2.228

Review 4.  Kidney Transplantation in Patients with HIV.

Authors:  Deirdre Sawinski
Journal:  Kidney360       Date:  2020-05-06

5.  Early steps to kidney transplantation among persons with HIV and end-stage renal disease in ESRD network 6.

Authors:  Ruth O Adekunle; Aneesh K Mehta; Zhengsheng Wang; Rachel E Patzer; Rebecca Zhang
Journal:  Transpl Infect Dis       Date:  2021-12-14       Impact factor: 2.228

  5 in total

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