| Literature DB >> 2892132 |
G Y Minamoto1, J W Gold, D A Scheinberg, W D Hardy, N Chein, E Zuckerman, L Reich, K Dietz, T Gee, J Hoffer.
Abstract
Among 211 adults with leukemia who received multiple transfusions, 6 were found to be seropositive for human T-cell leukemia virus Type I (HTLV-I). Before the positive serum specimens were obtained, these patients received a mean of 14 units of red cells and 78 units of platelets. Seroconversion could be documented in three patients. None of the 6 patients seropositive for HTLV-I had a T-cell leukemia, other illnesses attributable to HTLV-I infection, or risk factors for HTLV-I infection other than transfusion: none were seropositive for human immunodeficiency virus. Patients with leukemia who receive multiple transfusions appear to be at risk for HTLV-I infection.Entities:
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Year: 1988 PMID： 2892132 DOI： 10.1056/NEJM198801283180405
Source DB: PubMed Journal: N Engl J Med ISSN： 0028-4793 Impact factor: 91.245