Yuri Nakae1, Dai Horikawa1, Keiko Tamiya1, Akiyoshi Namiki2. 1. Department of Anesthesia, Hokkaido Children's Medical Center, 1-10-1 Zenibako, 047-0261, Otaru, Japan. 2. Department of Anesthesiology, Sapporo Medical University School of Medicine, South 1, West 16, Chuo-ku, 060-0061, Sapporo, Japan.
Abstract
PURPOSE: The aim of this study was to compare the effect of low-flow anesthesia with or without a heat and moisture exchanger with high-flow anesthesia on airway gas humidification in children. METHODS:One hundred twenty children were randomly assigned to one of three groups: low-flow anesthesia with 0.5l·min-1 of total gas flow (LFA,n=40), low-flow anesthesia with 0.5l·min-1 using a heat and moisture exchanger (HME,n=40), and high-flow anesthesia with 6l·min-1 (HFA,n=40). The temperature and relative humidity of the inspired gas were measured throughout anesthesia. RESULTS: The relative humidity of the inspired gas in the HME group was increased compared with that of the LFA and HFA groups 20 min after induction (p<0.05). The airway humidification in the LFA group was higher than that in the HFA group 10 min after induction (p<0.05). The temperature of the inspired gas in the HME group was increased compared with that in the LFA and HFA groups after 70 min (P<0.05). CONCLUSION: Low-flow anesthesia is less effective in providing adequate humidification of inspired gas than low-flow anesthesia with a heat and moisture exchanger, but significantly better than high-flow anesthesia in children.
RCT Entities:
PURPOSE: The aim of this study was to compare the effect of low-flow anesthesia with or without a heat and moisture exchanger with high-flow anesthesia on airway gas humidification in children. METHODS: One hundred twenty children were randomly assigned to one of three groups: low-flow anesthesia with 0.5l·min-1 of total gas flow (LFA,n=40), low-flow anesthesia with 0.5l·min-1 using a heat and moisture exchanger (HME,n=40), and high-flow anesthesia with 6l·min-1 (HFA,n=40). The temperature and relative humidity of the inspired gas were measured throughout anesthesia. RESULTS: The relative humidity of the inspired gas in the HME group was increased compared with that of the LFA and HFA groups 20 min after induction (p<0.05). The airway humidification in the LFA group was higher than that in the HFA group 10 min after induction (p<0.05). The temperature of the inspired gas in the HME group was increased compared with that in the LFA and HFA groups after 70 min (P<0.05). CONCLUSION: Low-flow anesthesia is less effective in providing adequate humidification of inspired gas than low-flow anesthesia with a heat and moisture exchanger, but significantly better than high-flow anesthesia in children.