Literature DB >> 28920978

A two-photon fluorescent probe for ratiometric imaging of endogenous hypochlorous acid in live cells and tissues.

Yong Woong Jun1, Sourav Sarkar, Subhankar Singha, Ye Jin Reo, Hye Rim Kim, Jong-Jin Kim, Young-Tae Chang, Kyo Han Ahn.   

Abstract

A fluorescent probe that enables ratiometric imaging of endogenous hypochlorous acid (HOCl) in cells and tissues by two-photon microscopy is developed based on a red-emitting acetyl-benzocoumarin (AcBC) dye. An oxathiolane group in the probe reacts with HOCl to generate the AcBC dye, which involves a ratiometric fluorescence change only toward HOCl along with high sensitivity.

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Year:  2017        PMID: 28920978     DOI: 10.1039/c7cc05834a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN: 1359-7345            Impact factor:   6.222


  7 in total

1.  Epileptic brain fluorescent imaging reveals apigenin can relieve the myeloperoxidase-mediated oxidative stress and inhibit ferroptosis.

Authors:  Chenwen Shao; Jiwen Yuan; Yani Liu; Yajuan Qin; Xueao Wang; Jin Gu; Guiquan Chen; Bing Zhang; Hong-Ke Liu; Jing Zhao; Hai-Liang Zhu; Yong Qian
Journal:  Proc Natl Acad Sci U S A       Date:  2020-04-23       Impact factor: 11.205

2.  An Excimer Clamp for Measuring Damaged-Base Excision by the DNA Repair Enzyme NTH1.

Authors:  Yong Woong Jun; David L Wilson; Anna M Kietrys; Elizabeth R Lotsof; Savannah G Conlon; Sheila S David; Eric T Kool
Journal:  Angew Chem Int Ed Engl       Date:  2020-03-17       Impact factor: 15.336

3.  Ratiometric fluorescent probes for capturing endogenous hypochlorous acid in the lungs of mice.

Authors:  Xinfu Zhang; Weiyu Zhao; Bin Li; Wenqing Li; Chengxiang Zhang; Xucheng Hou; Justin Jiang; Yizhou Dong
Journal:  Chem Sci       Date:  2018-09-05       Impact factor: 9.825

4.  Fluorescent probe for the detection of hypochlorous acid in water samples and cell models.

Authors:  Wandi Hu; Mei Zhao; Keyi Gu; Lianwu Xie; Mei Liu; Danqing Lu
Journal:  RSC Adv       Date:  2021-12-24       Impact factor: 3.361

5.  A novel fluorescent probe for imaging the process of HOCl oxidation and Cys/Hcy reduction in living cells.

Authors:  Zhen Liu; Guoping Li; Yana Wang; Jiulong Li; Yang Mi; Linna Guo; Wenjian Xu; Dapeng Zou; Tiesheng Li; Yangjie Wu
Journal:  RSC Adv       Date:  2018-03-05       Impact factor: 3.361

6.  Design of a ratiometric two-photon probe for imaging of hypochlorous acid (HClO) in wounded tissues.

Authors:  Zhiqiang Mao; Miantai Ye; Wei Hu; Xiaoxue Ye; Yanying Wang; Huijuan Zhang; Chunya Li; Zhihong Liu
Journal:  Chem Sci       Date:  2018-05-18       Impact factor: 9.825

Review 7.  Benzo[g]coumarin-Based Fluorescent Probes for Bioimaging Applications.

Authors:  Yuna Jung; Junyang Jung; Youngbuhm Huh; Dokyoung Kim
Journal:  J Anal Methods Chem       Date:  2018-06-14       Impact factor: 2.193

  7 in total

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