Literature DB >> 28917971

How Fast Is Protein-Ligand Association?

Stefano Gianni1, Per Jemth2.   

Abstract

There is increasing interest in studying protein interactions and their role in cell biology using kinetics. However, there is confusion about the proper terminology in terms of the distinction between rates and rate constants. We recommend a more stringent use of the words speed, fast, slow, rate, and rate constant.
Copyright © 2017 Elsevier Ltd. All rights reserved.

Keywords:  kinetics; ligand; protein binding; protein interactions; rate; rate constant

Mesh:

Substances:

Year:  2017        PMID: 28917971     DOI: 10.1016/j.tibs.2017.08.007

Source DB:  PubMed          Journal:  Trends Biochem Sci        ISSN: 0968-0004            Impact factor:   13.807


  2 in total

1.  Kinetic Methods of Deducing Binding Mechanisms Involving Intrinsically Disordered Proteins.

Authors:  Elin Karlsson; Per Jemth
Journal:  Methods Mol Biol       Date:  2021

2.  Quantitative mapping of protein-peptide affinity landscapes using spectrally encoded beads.

Authors:  Jagoree Roy; Björn Harink; Nikhil P Damle; Huy Quoc Nguyen; Naomi R Latorraca; Brian C Baxter; Kara Brower; Scott A Longwell; Tanja Kortemme; Kurt S Thorn; Martha S Cyert; Polly Morrell Fordyce
Journal:  Elife       Date:  2019-07-08       Impact factor: 8.140

  2 in total

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