Haiquan Xu1,2, Yanping Li1,3, Qian Zhang1, Xiaoqi L Hu1, Ailing Liu1, Songming Du1, Tingyu Li4, Hongwei Guo5, Ying Li6, Guifa Xu7, Weijia Liu8, Jun Ma9, Guansheng Ma1,10. 1. National Institute for Nutrition and Health, Chinese Center for Disease Control and Prevention, Beijing, China. 2. Institute of Food and Nutrition Development, Ministry of Agriculture, Beijing, China. 3. Department of Nutrition, Harvard T. H. Chan School of Public Health, Boston, MA, USA. 4. Chongqing Children's Hospital, Chongqing, China. 5. School of Public Health, Fudan University, Shanghai, China. 6. Harbin Medical University, Harbin, China. 7. Department of Public Health, Shandong University, Jinan, China. 8. Guangzhou Center for Disease Control and Prevention, Guangzhou, China. 9. Institute of Child and Adolescent Health, School of Public Health, Peking University, Beijing, China. 10. Department of Nutrition and Food Hygiene, School of Public Health, Peking University, Beijing, China. Email: mags@bjmu.edu.cn.
Abstract
BACKGROUND AND OBJECTIVES: With prevalence of childhood obesity increasing rapidly, developing of effective and sustainable intervention strategies is becoming more and more important for the prevention of childhood obesity in China. A trial was developed to evaluate the effect of comprehensive school-based intervention on childhood obesity. METHODS AND STUDY DESIGN: A multi-center cluster randomized controlled trial was conducted among urban children (n=9,867) aged 6-13 years in 38 primary schools from six large cities. Comprehensive intervention, nutrition education and physical activity interventions were carried out among children. Nutrition education was also targeted towards teachers, parents and health workers in intervention schools. The program was implemented for 2 semesters from May 2009 to May 2010. RESULTS: The combined prevalence of overweight and obesity increased by 1.5 percent (22.7% vs 24.2%, p<0.001) in control group while 0.2 percent in comprehensive intervention group (23.6% vs 23.8%, p=0.954) after intervention (p=0.067). The effect was significantly stronger among girls than boys (-1.4% vs -0.9%, p=0.028). A significant intervention effect was found on BMI for -0.3 kg/m2 (95% confidence interval (CI): -0.4, -0.2; p<0.001), BMI z scores for -0.14 (95% CI: -0.18, -0.11; p<0.001)，body fat for -0.8 percent (95% CI: -0.9, -0.6; p<0.001), waist circumference for -0.5 cm (95% CI: -0.6, -0.3; p<0.001), blood serum glucose for -0.20 mmol/L (95% CI: -0.24, -0.16; p<0.001) and cholesterol for -0.32 mmol/L (95% CI: -0.34, -0.30; p<0.001). CONCLUSIONS: We observed moderately significant effects on combined prevalence of overweight and obesity, BMI, BMI z scores, waist circumference, percentage body fat, glucose and lipid for a comprehensive school-based intervention of childhood obesity in China.
RCT Entities:
BACKGROUND AND OBJECTIVES: With prevalence of childhood obesity increasing rapidly, developing of effective and sustainable intervention strategies is becoming more and more important for the prevention of childhood obesity in China. A trial was developed to evaluate the effect of comprehensive school-based intervention on childhood obesity. METHODS AND STUDY DESIGN: A multi-center cluster randomized controlled trial was conducted among urban children (n=9,867) aged 6-13 years in 38 primary schools from six large cities. Comprehensive intervention, nutrition education and physical activity interventions were carried out among children. Nutrition education was also targeted towards teachers, parents and health workers in intervention schools. The program was implemented for 2 semesters from May 2009 to May 2010. RESULTS: The combined prevalence of overweight and obesity increased by 1.5 percent (22.7% vs 24.2%, p<0.001) in control group while 0.2 percent in comprehensive intervention group (23.6% vs 23.8%, p=0.954) after intervention (p=0.067). The effect was significantly stronger among girls than boys (-1.4% vs -0.9%, p=0.028). A significant intervention effect was found on BMI for -0.3 kg/m2 (95% confidence interval (CI): -0.4, -0.2; p<0.001), BMI z scores for -0.14 (95% CI: -0.18, -0.11; p<0.001)，body fat for -0.8 percent (95% CI: -0.9, -0.6; p<0.001), waist circumference for -0.5 cm (95% CI: -0.6, -0.3; p<0.001), blood serum glucose for -0.20 mmol/L (95% CI: -0.24, -0.16; p<0.001) and cholesterol for -0.32 mmol/L (95% CI: -0.34, -0.30; p<0.001). CONCLUSIONS: We observed moderately significant effects on combined prevalence of overweight and obesity, BMI, BMI z scores, waist circumference, percentage body fat, glucose and lipid for a comprehensive school-based intervention of childhood obesity in China.
Authors: Tamara Brown; Theresa Hm Moore; Lee Hooper; Yang Gao; Amir Zayegh; Sharea Ijaz; Martha Elwenspoek; Sophie C Foxen; Lucia Magee; Claire O'Malley; Elizabeth Waters; Carolyn D Summerbell Journal: Cochrane Database Syst Rev Date: 2019-07-23
Authors: Sacha R B Verjans-Janssen; Ilona van de Kolk; Dave H H Van Kann; Stef P J Kremers; Sanne M P L Gerards Journal: PLoS One Date: 2018-09-27 Impact factor: 3.240
Authors: Haiquan Xu; Yanping Li; Xianwen Shang; Songming Du; Qian Zhang; Ailing Liu; Guansheng Ma Journal: Int J Environ Res Public Health Date: 2020-12-01 Impact factor: 3.390
Authors: Haiquan Xu; Yanzhi Guo; Shijun Lu; Yunqian Ma; Xiuli Wang; Liyun Zhao; Junmao Sun Journal: Int J Environ Res Public Health Date: 2020-03-22 Impact factor: 3.390