M L Tárraga Marcos1, J M Panisello Royo2, J A Carbayo Herencia3, N Rosich Domenech4, J Alins Presas5, E Castell Panisello6, P J Tárraga López7. 1. DUE Residencia geriátrica, Albacete, España. 2. Medicina Interna, Hospital de Igualada, Igualada, Barcelona, España; Servicio de Nutrición, Hospital de Igualada, Igualada, Barcelona, España; Fundación para el Fomento de la Salud (FUFOSA), Madrid, España. 3. Unidad de Lípidos, Quirónsalud Hospital, Albacete, España; Departamento de Medicina Clínica, Universidad Miguel Hernández, Campus de Sant Joan, Alicante, España. 4. Servicio de Nutrición, Hospital de Igualada, Igualada, Barcelona, España; Fundación para el Fomento de la Salud (FUFOSA), Madrid, España. 5. Medicina de Familia y Comunitaria, ABS Abrera, Abrera, Barcelona, España. 6. Fundación para el Fomento de la Salud (FUFOSA), Madrid, España. 7. Fundación para el Fomento de la Salud (FUFOSA), Madrid, España; Medicina de Familia, EAP 5.A, Albacete, España; Facultad de Medicina, Universidad de Castilla La Mancha, Albacete, España. Electronic address: pjtarraga@sescam.jccm.es.
Abstract
OBJECTIVE: To analyse the effect of the use/implementation of 3methods to reduce weight in overweight or obese patients during one year of follow up. MATERIAL AND METHODS: The design corresponds to a double-blind, randomised, controlled clinical trial with 3arms, and 12 months of follow-up. Patients were randomised into 3intervention groups: obesity motivational intervention, with a nurse previously trained in motivational intervention by expert psychologists (G1; n=60); lower intensity consultation, non-motivational group, with digital platform support (G2; N=61), and a third group that received recommendations for weight loss and follow-up in Primary Care Clinic (G3; n=59). Anthropometric variables (weight, height, and abdominal-waist circumference) were measured, and the percentage of patients who managed to reduce their weight ≥5% was considered as the main measurement of treatment effectiveness. RESULTS: All groups significantly decreased body weight at the end of the study, with a reduction in G1 (-5.6kg) followed by G2 (-4.3kg), and G3 (-1.7kg), with an overall mean: -3.9kg. The indicators of clinical relevance were in G1/G3: relative risk (RR): 4.99 (95% CI: from 2.71 to 9.18); relative risk reduction (RRR): 399.1% (171.3 to 818.0); Absolute risk reduction (RAR): 65.3% (from 51.5 to 79.1) and NNT: 2 (from 2 to 2). In the G2/G3 groups: RR: 3.01 (from 1.57 to 5.76); RRR: 200.5% (from 57.0 to 475.5); RAR: 32.8% (from 16.9 to 48.7) and NNT: 4 (from 3 to 6). In the G1/G2 groups: RR: 1.66 (from 1.25 to 2.20); RRR: 66.1% (from 25.3 to 120.1); RAR: 32.5% (from 16.6 to 48.4) and NNT: 4 (from 3 to 7). CONCLUSIONS: All 3groups were able to reduce weight. Although the group with motivational intervention achieved the greatest decrease, as well as the most favourable clinical relevance indicators.
RCT Entities:
OBJECTIVE: To analyse the effect of the use/implementation of 3methods to reduce weight in overweight or obesepatients during one year of follow up. MATERIAL AND METHODS: The design corresponds to a double-blind, randomised, controlled clinical trial with 3arms, and 12 months of follow-up. Patients were randomised into 3intervention groups: obesity motivational intervention, with a nurse previously trained in motivational intervention by expert psychologists (G1; n=60); lower intensity consultation, non-motivational group, with digital platform support (G2; N=61), and a third group that received recommendations for weight loss and follow-up in Primary Care Clinic (G3; n=59). Anthropometric variables (weight, height, and abdominal-waist circumference) were measured, and the percentage of patients who managed to reduce their weight ≥5% was considered as the main measurement of treatment effectiveness. RESULTS: All groups significantly decreased body weight at the end of the study, with a reduction in G1 (-5.6kg) followed by G2 (-4.3kg), and G3 (-1.7kg), with an overall mean: -3.9kg. The indicators of clinical relevance were in G1/G3: relative risk (RR): 4.99 (95% CI: from 2.71 to 9.18); relative risk reduction (RRR): 399.1% (171.3 to 818.0); Absolute risk reduction (RAR): 65.3% (from 51.5 to 79.1) and NNT: 2 (from 2 to 2). In the G2/G3 groups: RR: 3.01 (from 1.57 to 5.76); RRR: 200.5% (from 57.0 to 475.5); RAR: 32.8% (from 16.9 to 48.7) and NNT: 4 (from 3 to 6). In the G1/G2 groups: RR: 1.66 (from 1.25 to 2.20); RRR: 66.1% (from 25.3 to 120.1); RAR: 32.5% (from 16.6 to 48.4) and NNT: 4 (from 3 to 7). CONCLUSIONS: All 3groups were able to reduce weight. Although the group with motivational intervention achieved the greatest decrease, as well as the most favourable clinical relevance indicators.
Authors: Claire D Madigan; Henrietta E Graham; Elizabeth Sturgiss; Victoria E Kettle; Kajal Gokal; Greg Biddle; Gemma M J Taylor; Amanda J Daley Journal: BMJ Date: 2022-05-30