Literature DB >> 28914259

Epigenetic targeting of Notch1-driven transcription using the HDACi panobinostat is a potential therapy against T-cell acute lymphoblastic leukemia.

M Waibel1,2,3, S J Vervoort1,2,3, I Y Kong4,5, S Heinzel4,5, K M Ramsbottom2, B P Martin1, E D Hawkins4,5, R W Johnstone1,2,3.   

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Year:  2017        PMID： 28914259     DOI： 10.1038/leu.2017.282

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  16 in total

1.  Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia.

Authors:  Andrew P Weng; Adolfo A Ferrando; Woojoong Lee; John P Morris; Lewis B Silverman; Cheryll Sanchez-Irizarry; Stephen C Blacklow; A Thomas Look; Jon C Aster
Journal:  Science       Date:  2004-10-08       Impact factor: 47.728

Review 2.  Anticancer activities of histone deacetylase inhibitors.

Authors:  Jessica E Bolden; Melissa J Peart; Ricky W Johnstone
Journal:  Nat Rev Drug Discov       Date:  2006-09       Impact factor: 84.694

3.  Manipulation of B-cell responses with histone deacetylase inhibitors.

Authors:  Michaela Waibel; Ailsa J Christiansen; Margaret L Hibbs; Jake Shortt; Sarah A Jones; Ian Simpson; Amanda Light; Kristy O'Donnell; Eric F Morand; David M Tarlinton; Ricky W Johnstone; Edwin D Hawkins
Journal:  Nat Commun       Date:  2015-04-27       Impact factor: 14.919

4.  c-Myc inhibition prevents leukemia initiation in mice and impairs the growth of relapsed and induction failure pediatric T-ALL cells.

Authors:  Justine E Roderick; Jessica Tesell; Leonard D Shultz; Michael A Brehm; Dale L Greiner; Marian H Harris; Lewis B Silverman; Stephen E Sallan; Alejandro Gutierrez; A Thomas Look; Jun Qi; James E Bradner; Michelle A Kelliher
Journal:  Blood       Date:  2014-01-06       Impact factor: 22.113

5.  PANORAMA 2: panobinostat in combination with bortezomib and dexamethasone in patients with relapsed and bortezomib-refractory myeloma.

Authors:  Paul G Richardson; Robert L Schlossman; Melissa Alsina; Donna M Weber; Steven E Coutre; Cristina Gasparetto; Sutapa Mukhopadhyay; Michael S Ondovik; Mahmudul Khan; Carole S Paley; Sagar Lonial
Journal:  Blood       Date:  2013-08-15       Impact factor: 22.113

6.  Panobinostat in combination with bortezomib in patients with relapsed or refractory peripheral T-cell lymphoma: an open-label, multicentre phase 2 trial.

Authors:  Daryl Tan; Colin Phipps; William Y K Hwang; Soo Yong Tan; Chun Hsien Yeap; Yiong Huak Chan; Kevin Tay; Soon Thye Lim; Yuh Shan Lee; Sathish Gopalakrishnan Kumar; Soo Chin Ng; S Fadilah; Won Seog Kim; Yeow Tee Goh
Journal:  Lancet Haematol       Date:  2015-07-07       Impact factor: 18.959

7.  Essential roles for ankyrin repeat and transactivation domains in induction of T-cell leukemia by notch1.

Authors:  J C Aster; L Xu; F G Karnell; V Patriub; J C Pui; W S Pear
Journal:  Mol Cell Biol       Date:  2000-10       Impact factor: 4.272

8.  Transcriptional upregulation of histone deacetylase 2 promotes Myc-induced oncogenic effects.

Authors:  G M Marshall; S Gherardi; N Xu; Z Neiron; T Trahair; C J Scarlett; D K Chang; P Y Liu; K Jankowski; N Iraci; M Haber; M D Norris; J Keating; E Sekyere; G Jonquieres; F Stossi; B S Katzenellenbogen; A V Biankin; G Perini; T Liu
Journal:  Oncogene       Date:  2010-08-09       Impact factor: 9.867

9.  Interconnecting molecular pathways in the pathogenesis and drug sensitivity of T-cell acute lymphoblastic leukemia.

Authors:  Takaomi Sanda; Xiaoyu Li; Alejandro Gutierrez; Yebin Ahn; Donna S Neuberg; Jennifer O'Neil; Peter R Strack; Christopher G Winter; Stuart S Winter; Richard S Larson; Harald von Boehmer; A Thomas Look
Journal:  Blood       Date:  2009-12-09       Impact factor: 22.113

Review 10.  Acute lymphoblastic leukaemia.

Authors:  Ching-Hon Pui; Leslie L Robison; A Thomas Look
Journal:  Lancet       Date:  2008-03-22       Impact factor: 79.321
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  11 in total

1.  Romidepsin enhances the efficacy of cytarabine in vivo, revealing histone deacetylase inhibition as a promising therapeutic strategy for KMT2A-rearranged infant acute lymphoblastic leukemia.

Authors:  Laurence C Cheung; Mark N Cruickshank; Anastasia M Hughes; Sajla Singh; Grace-Alyssa Chua; Jette Ford; Emanuela Ferrari; Joyce Oommen; Sébastien Malinge; Richard B Lock; Ursula R Kees; Rishi S Kotecha
Journal:  Haematologica       Date:  2019-01-24       Impact factor: 9.941

Review 2.  T-cell Acute Lymphoblastic Leukemia: A Roadmap to Targeted Therapies.

Authors:  Valentina Cordo'; Jordy C G van der Zwet; Kirsten Canté-Barrett; Rob Pieters; Jules P P Meijerink
Journal:  Blood Cancer Discov       Date:  2020-11-24

3.  Epigenetic modulators of B cell fate identified through coupled phenotype-transcriptome analysis.

Authors:  Stephin J Vervoort; Edwin D Hawkins; Isabella Y Kong; Stephanie Trezise; Amanda Light; Izabela Todorovski; Gisela Mir Arnau; Sreeja Gadipally; David Yoannidis; Kaylene J Simpson; Xueyi Dong; Lachlan Whitehead; Jessica C Tempany; Anthony J Farchione; Amania A Sheikh; Joanna R Groom; Kelly L Rogers; Marco J Herold; Vanessa L Bryant; Matthew E Ritchie; Simon N Willis; Ricky W Johnstone; Philip D Hodgkin; Stephen L Nutt
Journal:  Cell Death Differ       Date:  2022-07-13       Impact factor: 12.067

4.  Chidamide inhibits the NOTCH1-MYC signaling axis in T-cell acute lymphoblastic leukemia.

Authors:  Mengping Xi; Shanshan Guo; Caicike Bayin; Sophie Rousseaux; Saadi Khochbin; Jian-Qing Mi; Jin Wang; Lijun Peng; Florent Chuffart; Ekaterina Bourova-Flin
Journal:  Front Med       Date:  2021-10-20       Impact factor: 9.927

5.  Aurora B kinase as a therapeutic target in acute lymphoblastic leukemia.

Authors:  Hiroaki Goto; Yuki Yoshino; Mieko Ito; Junichi Nagai; Tadashi Kumamoto; Takesi Inukai; Yukari Sakurai; Naoyuki Miyagawa; Dai Keino; Tomoko Yokosuka; Fuminori Iwasaki; Satoshi Hamanoue; Masae Shiomi; Shoko Goto
Journal:  Cancer Chemother Pharmacol       Date:  2020-03-06       Impact factor: 3.333

6.  Defining the in vivo characteristics of acute myeloid leukemia cells behavior by intravital imaging.

Authors:  Delfim Duarte; Saoirse Amarteifio; Heather Ang; Isabella Y Kong; Nicola Ruivo; Gunnar Pruessner; Edwin D Hawkins; Cristina Lo Celso
Journal:  Immunol Cell Biol       Date:  2018-12-13       Impact factor: 5.126

7.  Clinicopathological Characteristics and Mutational Profiling of Adult T-Cell Lymphoblastic Lymphoma in a Chinese Population.

Authors:  Feili Chen; Diwen Pang; Hanguo Guo; Xinmiao Jiang; Sichu Liu; Ling Huang; Xiaojuan Wei; Zhanli Liang; Xiaoxia Wang; Wenyu Li
Journal:  Cancer Manag Res       Date:  2020-04-30       Impact factor: 3.989

8.  Integrative Network Analysis of Differentially Methylated and Expressed Genes for Biomarker Identification in Leukemia.

Authors:  Robersy Sanchez; Sally A Mackenzie
Journal:  Sci Rep       Date:  2020-02-07       Impact factor: 4.379

9.  Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML.

Authors:  Delfim Duarte; Edwin D Hawkins; Olufolake Akinduro; Heather Ang; Katia De Filippo; Isabella Y Kong; Myriam Haltalli; Nicola Ruivo; Lenny Straszkowski; Stephin J Vervoort; Catriona McLean; Tom S Weber; Reema Khorshed; Chiara Pirillo; Andrew Wei; Saravana K Ramasamy; Anjali P Kusumbe; Ken Duffy; Ralf H Adams; Louise E Purton; Leo M Carlin; Cristina Lo Celso
Journal:  Cell Stem Cell       Date:  2017-12-21       Impact factor: 24.633

10.  Discrimination of DNA Methylation Signal from Background Variation for Clinical Diagnostics.

Authors:  Robersy Sanchez; Xiaodong Yang; Thomas Maher; Sally A Mackenzie
Journal:  Int J Mol Sci       Date:  2019-10-27       Impact factor: 5.923
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