| Literature DB >> 28913605 |
Jan Claassen1, Joshua N Goldstein2.
Abstract
Patients with prolonged or rapidly recurring convulsions lasting more than 5 min should be considered to be in status epilepticus (SE) and receive immediate resuscitation. Although there are few randomized clinical trials, available evidence and experience suggest that early and aggressive treatment of SE improves patient outcomes, for which reason this was chosen as an Emergency Neurological Life Support protocol. The current approach to the emergency treatment of SE emphasizes rapid initiation of adequate doses of first line therapy, as well as accelerated second line anticonvulsant drugs and induced coma when these fail, coupled with admission to a unit capable of neurological critical care and electroencephalography monitoring. This protocol will focus on the initial treatment of SE but also review subsequent steps in the protocol once the patient is hospitalized.Entities:
Keywords: Anticonvulsant; EEG monitoring; Pharmacologic coma; Protocol; Seizures; Status epilepticus
Mesh:
Year: 2017 PMID: 28913605 DOI: 10.1007/s12028-017-0460-1
Source DB: PubMed Journal: Neurocrit Care ISSN: 1541-6933 Impact factor: 3.210