Literature DB >> 28913501

Acute poisoning due to ingestion of Datura stramonium - a case report.

Sebastian Daniel Trancă1, Robert Szabo2, Mihaela Cociş1.   

Abstract

Datura stramonium (DS) is a widespread annual plant, containing atropine, hyoscyamine, and scopolamine, which can produce poisoning with a severe anticholinergic syndrome. Teenagers ingest the roots, seeds or the entire plant to obtain its hallucinogenic and euphoric effects. We presented the case of a 22 year old male who was admitted to the Emergency Room in a coma after consuming Datura stramonium, 2 hours earlier. The patient presented with fever, tachycardia with right bundle branch block, and urinary retention. Rapid sequence induction and intubation was performed immediately, with sedation and assisted-control mechanical ventilation, after being transferred to the Intensive Care Unit. The patient received activated charcoal, in repeated doses, external and internal cooling was applied, and an infusion of neostigmine was started. The biological assessment revealed rhabdomyolysis and prevention of renal failure was initiated. After a proper neurological evaluation, 36 hours after using Datura stramonium, the patient was extubated and transferred to the Psychiatric ward for further assessment and care.

Entities:  

Keywords:  Datura stramonium; anticholinergic syndrome; coma; toxic delirium

Year:  2017        PMID: 28913501      PMCID: PMC5555431          DOI: 10.21454/rjaic.7518.241.szb

Source DB:  PubMed          Journal:  Rom J Anaesth Intensive Care        ISSN: 2392-7518


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  4 in total

1.  Modulation of immunological responses by aqueous extract of Datura stramonium L. seeds on cyclophosphamide-induced immunosuppression in Wistar rats.

Authors:  Parker Elijah Joshua; Junaidu Yahaya; Daniel Emmanuel Ekpo; Joyce Oloaigbe Ogidigo; Arome Solomon Odiba; Rita Onyekachukwu Asomadu; Samson Ayodeji Oka; Olasupo Stephen Adeniyi
Journal:  BMC Immunol       Date:  2022-10-19       Impact factor: 3.594

Review 2.  Bioprospecting Plant Growth Promoting Rhizobacteria for Enhancing the Biological Properties and Phytochemical Composition of Medicinally Important Crops.

Authors:  Asfa Rizvi; Bilal Ahmed; Mohammad Saghir Khan; Hossam S El-Beltagi; Shahid Umar; Jintae Lee
Journal:  Molecules       Date:  2022-02-19       Impact factor: 4.411

3.  Multiple organ toxicity of Datura stramonium seed extracts.

Authors:  Temidayo Ogunmoyole; Racheal Imoleayo Adeyeye; Beatrice Oluwatosin Olatilu; Olubukola Abidemi Akande; Oluwadare Joel Agunbiade
Journal:  Toxicol Rep       Date:  2019-09-24

4.  Unknowing ingestion of Brugmansia suaveolens leaves presenting with signs of anticholinergic toxicity: a case report.

Authors:  K P Jayawickreme; K V C Janaka; S A S P Subasinghe
Journal:  J Med Case Rep       Date:  2019-10-30
  4 in total

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