Literature DB >> 28913274

Primary Cutaneous Mucinous Carcinoma Treated with Narrow Surgical Margin.

Jin-Hee Choi1, Seung Chan Kim1, Jiye Kim1, Yoon Kyu Chung1.   

Abstract

Primary cutaneous mucinous carcinoma (PCMC) is a rare malignant tumor of eccrine origin. Clinically, the carcinoma presents as a solitary, slow growing, and painless nodule. For this reason, this tumor is often considered to be a benign mass in the preoperative setting. The lesion is, however, malignant in nature and has a tendency for local recurrence and infrequent metastasis. Wide local excision is the treatment of choice. However, few reports exist with information regarding surgical margins and clinical outcomes. Herein, we report a case of PCMC excised with a narrow surgical margin and review the relevant literature. A 49-year-old man presented with a small cutaneous nodule of the right cheek. The mass was excised without any margin, but pathologic examination revealed histology of mucinous carcinoma. Because of this, the operative site was re-excised with a 5-mm margin, and the wound was closed using a V-Y advancement flap. Systemic work-up did not reveal other potential metastatic primary, for a final diagnosis of PCMC. We report this case of PCMC, treated with relatively narrow margin in a patient with good prognostic factors.

Entities:  

Keywords:  Adenocarcinoma; Mucinous adenocarcinoma; Primary mucinous carcinoma

Year:  2016        PMID: 28913274      PMCID: PMC5556805          DOI: 10.7181/acfs.2016.17.3.158

Source DB:  PubMed          Journal:  Arch Craniofac Surg        ISSN: 2287-1152


  4 in total

1.  Mucin-secreting tumours of the skin with special reference to the so-called mixed-salivary tumour of the skin and its relation to hidradenoma.

Authors:  B LENNOX; A G E PEARSE; H G H RICHARDS
Journal:  J Pathol Bacteriol       Date:  1952-10

Review 2.  Primary cutaneous mucinous carcinoma: a systematic review and meta-analysis of outcomes after surgery.

Authors:  Loebat Kamalpour; Renata T Brindise; Michael Nodzenski; Daniel Q Bach; Emir Veledar; Murad Alam
Journal:  JAMA Dermatol       Date:  2014-04       Impact factor: 10.282

Review 3.  Primary mucinous carcinoma of the skin: the Mayo Clinic experience over the past 2 decades.

Authors:  Jessica A Adefusika; Jason D Pimentel; Rahul N Chavan; Jerry D Brewer
Journal:  Dermatol Surg       Date:  2015-02       Impact factor: 3.398

4.  Correlation between tumor-associated glycoprotein 72 mucin levels in tumor and serum of colorectal patients as measured by the quantitative CA 72-4 immunoassay.

Authors:  F Guadagni; M Roselli; M Cosimelli; A Spila; F Cavaliere; M Tedesco; R Arcuri; M R Abbolito; V Casale; M N Pericoli; A Vecchione; C U Casciani; J W Greiner; J Schlom
Journal:  Cancer Res       Date:  1996-11-15       Impact factor: 12.701

  4 in total
  2 in total

Review 1.  Current Treatment Options for Cutaneous Adnexal Malignancies.

Authors:  Hiroyuki Goto
Journal:  Curr Treat Options Oncol       Date:  2022-03-26

2.  Mucinous Adenocarcinoma of the Scalp: Primary Cutaneous Neoplasm Versus Underlying Metastatic Disease.

Authors:  Ciara A Brown; Michael C Lynch; Cristiane M Ueno
Journal:  Plast Reconstr Surg Glob Open       Date:  2018-04-16
  2 in total

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