Literature DB >> 28912615

Why the moratorium on human-animal chimera research should not be lifted.

Alan Moy1,2.   

Abstract

The National Institutes of Health (NIH) announced its plans to lift its moratorium on funding research that involves injecting human embryonic stem cells into animal embryos, which would allow for the creation of part-human and part-animal organisms known as chimeras. The NIH allowed only one month to receive public comments in the midst of a presidential election campaign. Lifting the moratorium means that, for the first time, the federal government will begin spending taxpayer dollars on the creation and manipulation of new organisms that would blur the line between humans and animals. Interestingly, this government effort is creating an uncommon coalition between pro-life groups and animal rights activists that oppose this medical research on ethical grounds; the former seeking to ensure the welfare of human embryos and the latter seeking to protect the well-being of animals. Unlike the issue of abortion, this research is complex. Yet, it is important that the pro-life laity and clergy be adequately informed on some of the basic science and ethics that surround this research. To fully understand why this research is unethical and why the NIH is pursuing this particular research, it is important to understand the ethical tenets governing human-subject research and why secular scientists are pursuing this scientific field.

Entities:  

Year:  2017        PMID: 28912615      PMCID: PMC5592304          DOI: 10.1080/00243639.2017.1293931

Source DB:  PubMed          Journal:  Linacre Q        ISSN: 0024-3639


  8 in total

1.  NIH and human embryo research revisited: what is wrong with this picture?

Authors:  D N Irving
Journal:  Linacre Q       Date:  2000-05

2.  Revolution postponed.

Authors:  Stephen S Hall
Journal:  Sci Am       Date:  2010-10       Impact factor: 2.142

3.  STEM CELLS. NIH debates human-animal chimeras.

Authors:  Gretchen Vogel
Journal:  Science       Date:  2015-10-16       Impact factor: 47.728

4.  Gene therapy is facing a crucial hearing.

Authors:  Gardiner Harris
Journal:  N Y Times Web       Date:  2005-03-03

Review 5.  Status of fetal tissue transplantation for the treatment of advanced Parkinson disease.

Authors:  Paul E Greene; Stanley Fahn
Journal:  Neurosurg Focus       Date:  2002-11-15       Impact factor: 4.047

Review 6.  The value and limitations of transgenic mouse models used in drug discovery for Alzheimer's disease: an update.

Authors:  Kelly R Bales
Journal:  Expert Opin Drug Discov       Date:  2012-02-23       Impact factor: 6.098

7.  Interspecies Chimerism with Mammalian Pluripotent Stem Cells.

Authors:  Jun Wu; Aida Platero-Luengo; Masahiro Sakurai; Atsushi Sugawara; Maria Antonia Gil; Takayoshi Yamauchi; Keiichiro Suzuki; Yanina Soledad Bogliotti; Cristina Cuello; Mariana Morales Valencia; Daiji Okumura; Jingping Luo; Marcela Vilariño; Inmaculada Parrilla; Delia Alba Soto; Cristina A Martinez; Tomoaki Hishida; Sonia Sánchez-Bautista; M Llanos Martinez-Martinez; Huili Wang; Alicia Nohalez; Emi Aizawa; Paloma Martinez-Redondo; Alejandro Ocampo; Pradeep Reddy; Jordi Roca; Elizabeth A Maga; Concepcion Rodriguez Esteban; W Travis Berggren; Estrella Nuñez Delicado; Jeronimo Lajara; Isabel Guillen; Pedro Guillen; Josep M Campistol; Emilio A Martinez; Pablo Juan Ross; Juan Carlos Izpisua Belmonte
Journal:  Cell       Date:  2017-01-26       Impact factor: 41.582

Review 8.  Human-animal chimeras: ethical issues about farming chimeric animals bearing human organs.

Authors:  Rodolphe Bourret; Eric Martinez; François Vialla; Chloé Giquel; Aurélie Thonnat-Marin; John De Vos
Journal:  Stem Cell Res Ther       Date:  2016-06-29       Impact factor: 6.832

  8 in total
  1 in total

1.  The American Public Is Ready to Accept Human-Animal Chimera Research.

Authors:  Andrew T Crane; Francis X Shen; Jennifer L Brown; Warren Cormack; Mercedes Ruiz-Estevez; Joseph P Voth; Tsutomu Sawai; Taichi Hatta; Misao Fujita; Walter C Low
Journal:  Stem Cell Reports       Date:  2020-10-01       Impact factor: 7.765

  1 in total

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