| Literature DB >> 28912047 |
F Bortolotti1, D Sorio2, A Bertaso2, F Tagliaro3.
Abstract
The need for investigating alcohol abuse by means of objective tools is worldwide accepted. Among the currently available biomarkers of chronic alcohol abuse, carbohydrate-deficient transferrin (CDT) is one of the most used indicator, mainly because of its high specificity. However, some CDT analytical and interpretation aspects are still under discussion, as witnessed by numerous research papers and reviews. The present article presents a critical review of the literature on CDT appeared in the period from 2007 to 2017 (included). The article is organized in the following sections: (1) introduction, (2) pre-analytical aspects (3) analytical aspects (4) diagnostic aspects (5) concluding remarks. As many as 139 papers appeared in the international literature and retrieved by the search engines PubMed, Web of Science and Scopus are quoted.Entities:
Keywords: Analytical methods; Biomarkers of alcohol abuse; Carbohydrate deficient transferrin; Diagnostic sensitivity; Diagnostic specificity
Mesh：
Substances：
Year: 2017 PMID： 28912047 DOI： 10.1016/j.jpba.2017.09.006
Source DB: PubMed Journal: J Pharm Biomed Anal ISSN： 0731-7085 Impact factor: 3.935