Literature DB >> 28911318

Development and Optimization of a High Titer Recombinant Lentivirus System.

Austin Storck1, James Ludtke1, Leisha Kopp1, Laura Juckem1.   

Abstract

To enable simple and effective high titer recombinant lentivirus production, we examined key parameters for the generation of lentivirus including: transfection optimization, media change, incubation time and DNA vector selection. These results illustrate the importance of optimizing transfection processes for high titer recombinant lentivirus production.

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Year:  2017        PMID: 28911318     DOI: 10.2144/000114590

Source DB:  PubMed          Journal:  Biotechniques        ISSN: 0736-6205            Impact factor:   1.993


  2 in total

1.  Development of a laboratory scalable process for enhancing lentivirus production by transient transfection of HEK293 adherent cultures.

Authors:  Y K Ho; H P Too
Journal:  Gene Ther       Date:  2020-04-27       Impact factor: 5.250

2.  Therapeutical Significance of Serpina3n Subsequent Cerebral Ischemia via Cytotoxic Granzyme B Inactivation.

Authors:  Mehwish Saba Aslam; Mobeena Saba Aslam; Komal Saba Aslam; Asia Iqbal; Liudi Yuan
Journal:  Biomed Res Int       Date:  2022-05-29       Impact factor: 3.246

  2 in total

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