W-C Lee1, S Kopetz2, I I Wistuba3,4, J Zhang1,4. 1. Department of Genomic Medicine. 2. Department of Gastrointestinal Medical Oncology. 3. Department of Translational Molecular Pathology. 4. Department of Thoracic/Head and Neck Medical Oncology, University of Texas MD Anderson Cancer Center, Houston, USA.