Literature DB >> 28902341

Bilateral Retinal Detachments After Intravitreal Injection of Adipose-Derived 'Stem Cells' in a Patient With Exudative Macular Degeneration.

Steven S Saraf, Matthew A Cunningham, Ajay E Kuriyan, Sarah P Read, Philip J Rosenfeld, Harry W Flynn, Thomas A Albini.   

Abstract

A 77-year-old woman with exudative macular degeneration underwent bilateral intravitreal injections of "stem cells" at a clinic in Georgia. One month and 3 months after injection, she developed retinal detachments in the left and right eyes, respectively. Increased awareness within the medical community of such poor outcomes is critical so that clinics offering untested practices that have been shown to be potentially harmful to patients can be identified and brought under U.S. Food and Drug Administration oversight. [Ophthalmic Surg Lasers Imaging Retina. 2017;48:772-775.].
© 2017 [Saraf, Cunningham, Kuriyan, et al.].

Entities:  

Mesh：

Year:  2017        PMID： 28902341     DOI： 10.3928/23258160-20170829-16

Source DB:  PubMed          Journal:  Ophthalmic Surg Lasers Imaging Retina        ISSN： 2325-8160            Impact factor:   1.300


  17 in total

1.  Assessing "Cell Therapy" Clinics Offering Treatments of Ocular Conditions using Direct-to-Consumer Marketing Websites in the United States.

Authors:  Rajinder S Nirwan; Thomas A Albini; Jayanth Sridhar; Harry W Flynn; Ajay E Kuriyan
Journal:  Ophthalmology       Date:  2019-03-21       Impact factor: 12.079

Review 2.  Retinal stem cell transplantation: Balancing safety and potential.

Authors:  Mandeep S Singh; Susanna S Park; Thomas A Albini; M Valeria Canto-Soler; Henry Klassen; Robert E MacLaren; Masayo Takahashi; Aaron Nagiel; Steven D Schwartz; Kapil Bharti
Journal:  Prog Retin Eye Res       Date:  2019-09-05       Impact factor: 21.198

Review 3.  STEM CELL THERAPIES, GENE-BASED THERAPIES, OPTOGENETICS, AND RETINAL PROSTHETICS: Current State and Implications for the Future.

Authors:  Edward H Wood; Peter H Tang; Irina De la Huerta; Edward Korot; Stephanie Muscat; Daniel A Palanker; George A Williams
Journal:  Retina       Date:  2019-05       Impact factor: 4.256

4.  Concentrated Conditioned Media from Adipose Tissue Derived Mesenchymal Stem Cells Mitigates Visual Deficits and Retinal Inflammation Following Mild Traumatic Brain Injury.

Authors:  Kumar Abhiram Jha; Mickey Pentecost; Raji Lenin; Lada Klaic; Sally L Elshaer; Jordy Gentry; John M Russell; Alex Beland; Anton Reiner; Veronique Jotterand; Nicolas Sohl; Rajashekhar Gangaraju
Journal:  Int J Mol Sci       Date:  2018-07-11       Impact factor: 5.923

Review 5.  Looking into the future: Gene and cell therapies for glaucoma.

Authors:  András M Komáromy; Kristin L Koehl; Shin Ae Park
Journal:  Vet Ophthalmol       Date:  2021-01-07       Impact factor: 1.644

6.  Unproven stem cell therapy for macular degeneration.

Authors:  Zubair A Ansari; Ajay E Kuriyan; Thomas A Albini
Journal:  Oncotarget       Date:  2017-10-19

7.  Allogeneic iPSC-Derived RPE Cell Graft Failure Following Transplantation Into the Subretinal Space in Nonhuman Primates.

Authors:  Trevor J McGill; Jonathan Stoddard; Lauren M Renner; Ilhem Messaoudi; Kapil Bharti; Shoukhrat Mitalipov; Andreas Lauer; David J Wilson; Martha Neuringer
Journal:  Invest Ophthalmol Vis Sci       Date:  2018-03-01       Impact factor: 4.799

8.  Adipose stem cells and their paracrine factors are therapeutic for early retinal complications of diabetes in the Ins2Akita mouse.

Authors:  Sally L Elshaer; William Evans; Mickey Pentecost; Raji Lenin; Ramesh Periasamy; Kumar Abhiram Jha; Shanta Alli; Jordy Gentry; Samuel M Thomas; Nicolas Sohl; Rajashekhar Gangaraju
Journal:  Stem Cell Res Ther       Date:  2018-11-21       Impact factor: 6.832

Review 9.  Enduring Neuroprotective Effect of Subacute Neural Stem Cell Transplantation After Penetrating TBI.

Authors:  Anelia A Y Kassi; Anil K Mahavadi; Angelica Clavijo; Daniela Caliz; Stephanie W Lee; Aminul I Ahmed; Shoji Yokobori; Zhen Hu; Markus S Spurlock; Joseph M Wasserman; Karla N Rivera; Samuel Nodal; Henry R Powell; Long Di; Rolando Torres; Lai Yee Leung; Andres Mariano Rubiano; Ross M Bullock; Shyam Gajavelli
Journal:  Front Neurol       Date:  2019-01-17       Impact factor: 4.086

10.  Human Umbilical Cord Mesenchymal Stem Cells Attenuate Ocular Hypertension-Induced Retinal Neuroinflammation via Toll-Like Receptor 4 Pathway.

Authors:  Shangli Ji; Jie Xiao; Jian Liu; Shibo Tang
Journal:  Stem Cells Int       Date:  2019-10-15       Impact factor: 5.443
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