Literature DB >> 28900650

Sensitive detection of microRNAs by duplex specific nuclease-assisted target recycling and pyrene excimer switching.

Fei Ma1, Wen-Jing Liu, Qianyi Zhang, Chun-Yang Zhang.   

Abstract

Herein, we develop a simple fluorescence method for the sensitive detection of microRNAs based on duplex specific nuclease-assisted target recycling and pyrene excimer switching. This method is extremely sensitive with a detection limit of 0.58 fM, and it can be applied to absolutely detect endogenous microRNAs in cancer cells, holding great potential for clinical diagnosis and biomedical research studies.

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Year:  2017        PMID： 28900650     DOI： 10.1039/c7cc06290g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  3 in total

1.  A label-free aptamer-based biosensor for microRNA detection by the RNA-regulated fluorescence of malachite green.

Authors:  Honghong Wang; Hui Wang; Mai Zhang; Yuting Jia; Zhengping Li
Journal:  RSC Adv       Date:  2019-10-15       Impact factor: 4.036

2.  Signal amplification method for miR-205 assay through combining graphene oxide with duplex-specific nuclease.

Authors:  Zhaoqi Yang; Lan Qin; Dutao Yang; Weixia Chen; Yue Qian; Jian Jin
Journal:  RSC Adv       Date:  2019-08-30       Impact factor: 4.036

3.  Methyl Viologens of Bis-(4'-Pyridylethynyl)Arenes - Structures, Photophysical and Electrochemical Studies, and their Potential Application in Biology.

Authors:  Goutam Kumar Kole; Marta Košćak; Anissa Amar; Dragomira Majhen; Ksenija Božinović; Zlatko Brkljaca; Matthias Ferger; Evripidis Michail; Sabine Lorenzen; Alexandra Friedrich; Ivo Krummenacher; Michael Moos; Holger Braunschweig; Abdou Boucekkine; Christoph Lambert; Jean-François Halet; Ivo Piantanida; Klaus Müller-Buschbaum; Todd B Marder
Journal:  Chemistry       Date:  2022-05-30       Impact factor: 5.020
  3 in total

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