Literature DB >> 28900583

The Daniel K. Inouye College of Pharmacy Scripts: Precision Medicine Through the Use of Pharmacogenomics: Current Status and Barriers to Implementation.

Anita E Ciarleglio1, Carolyn Ma2.   

Abstract

The precision medicine initiative brought forth by President Barack Obama in 2015 is an important step on the journey to truly personalized medicine. A broad knowledge and understanding of the implications of the pharmacogenomic literature will be critical to the achievement of this goal. While a great amount of data has been published in the areas of pharmacogenomics and pharmacogenetics, there are still relatively few instances in which the need for clinical intervention can be stated without doubt, and which are widely accepted and practiced by the medical community. As our knowledge base rapidly expands, issues such as insurance reimbursement for genetic testing and education of the health care workforce will be paramount to achieving the goal of precision medicine for all patients.

Entities:  

Keywords:  pharmacogenetics; pharmacogenomics; precision medicine

Mesh:

Year:  2017        PMID: 28900583      PMCID: PMC5592383     

Source DB:  PubMed          Journal:  Hawaii J Med Public Health        ISSN: 2165-8242


  19 in total

1.  Medical genetics: a marker for Stevens-Johnson syndrome.

Authors:  Wen-Hung Chung; Shuen-Iu Hung; Hong-Shang Hong; Mo-Song Hsih; Li-Cheng Yang; Hsin-Chun Ho; Jer-Yuarn Wu; Yuan-Tsong Chen
Journal:  Nature       Date:  2004-04-01       Impact factor: 49.962

2.  Codeine, ultrarapid-metabolism genotype, and postoperative death.

Authors:  Catherine Ciszkowski; Parvaz Madadi; Michael S Phillips; Albert E Lauwers; Gideon Koren
Journal:  N Engl J Med       Date:  2009-08-20       Impact factor: 91.245

Review 3.  Genetics in the Clinical Decision of Antiplatelet Treatment.

Authors:  Gerasimos Siasos; Marina Zaromitidou; Evangelos Oikonomou; Manolis Vavuranakis; Vicky Tsigkou; Nikolaos Papageorgiou; Dimitrios Chaniotis; Dimitrios A Vrachatis; Christodoulos Stefanadis; Athanasios G Papavassiliou; Dimitrios Tousoulis
Journal:  Curr Pharm Des       Date:  2017       Impact factor: 3.116

Review 4.  Role of genetic testing in patients undergoing percutaneous coronary intervention.

Authors:  Jae Youn Moon; Francesco Franchi; Fabiana Rollini; Jose R Rivas Rios; Megha Kureti; Larisa H Cavallari; Dominick J Angiolillo
Journal:  Expert Rev Clin Pharmacol       Date:  2017-10-12       Impact factor: 5.045

5.  Finishing the euchromatic sequence of the human genome.

Authors: 
Journal:  Nature       Date:  2004-10-21       Impact factor: 49.962

6.  Clinical Pharmacogenetics Implementation Consortium guidelines for CYP2C19 genotype and clopidogrel therapy: 2013 update.

Authors:  S A Scott; K Sangkuhl; C M Stein; J-S Hulot; J L Mega; D M Roden; T E Klein; M S Sabatine; J A Johnson; A R Shuldiner
Journal:  Clin Pharmacol Ther       Date:  2013-05-22       Impact factor: 6.875

7.  A randomized controlled trial to assess the efficacy and safety of doubling dose clopidogrel versus ticagrelor for the treatment of acute coronary syndrome in patients with CYP2C19*2 homozygotes.

Authors:  Ran Xiong; Wenxian Liu; Liying Chen; Tieduo Kang; Shangqiu Ning; Jiang Li
Journal:  Int J Clin Exp Med       Date:  2015-08-15

Review 8.  The IGNITE Pharmacogenetics Working Group: An Opportunity for Building Evidence with Pharmacogenetic Implementation in a Real-World Setting.

Authors:  L H Cavallari; A L Beitelshees; K V Blake; L G Dressler; J D Duarte; A Elsey; J N Eichmeyer; P E Empey; J P Franciosi; J K Hicks; A M Holmes; Ljb Jeng; C R Lee; J J Lima; N A Limdi; J Modlin; A O Obeng; N Petry; V M Pratt; T C Skaar; S Tuteja; D Voora; M Wagner; K W Weitzel; R A Wilke; J F Peterson; J A Johnson
Journal:  Clin Transl Sci       Date:  2017-03-14       Impact factor: 4.689

9.  Analysis of Genetic Variation in CYP450 Genes for Clinical Implementation.

Authors:  Liuh Ling Goh; Chia Wei Lim; Wey Cheng Sim; Li Xian Toh; Khai Pang Leong
Journal:  PLoS One       Date:  2017-01-03       Impact factor: 3.240

10.  Multiple evidence strands suggest that there may be as few as 19,000 human protein-coding genes.

Authors:  Iakes Ezkurdia; David Juan; Jose Manuel Rodriguez; Adam Frankish; Mark Diekhans; Jennifer Harrow; Jesus Vazquez; Alfonso Valencia; Michael L Tress
Journal:  Hum Mol Genet       Date:  2014-06-16       Impact factor: 6.150

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