| Literature DB >> 28899105 |
Brett Williams1, Mimi Ghosh2, Charles A B Boucher3, Frederic Bushman4, Stacy Carrington-Lawrence5, Ronald G Collman6, Satya Dandekar7, Que Dang8, Angela Malaspina8, Roger Paredes9, Cara C Wilson10, Piotr Nowak11, Nichole R Klatt12, Laurel Lagenaur13, Alan L Landay14.
Abstract
Commensal organisms appear to play significant roles in normal homeostasis as well as in the pathogenesis of HIV infection in a number of different organ systems. On November 17th and 18th, 2016, leading researchers from around the world met to discuss their insights on advances in our understanding of HIV and the microbiome at the National Institutes of Health (NIH) in Bethesda. Dr. Elhanan Borenstein of the University of Washington gave a keynote address where he discussed new developments in systems biology which hold the promise of illuminating the pathways by which these organisms interact with human physiology. He suggested that we need to get past correlations in microbiome research by using models and informatics which incorporate metagenomics to predict functional changes in the microbiome.Entities:
Keywords: HIV; HIV transmission; inflammation; microbial translocation
Mesh:
Year: 2017 PMID: 28899105 PMCID: PMC5770117 DOI: 10.1089/aid.2017.0137
Source DB: PubMed Journal: AIDS Res Hum Retroviruses ISSN: 0889-2229 Impact factor: 2.205