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Literature DB >> 28898625

Discovery of a Biomarker and Lead Small Molecules to Target r(GGGGCC)-Associated Defects in c9FTD/ALS.

Zhaoming Su, Yongjie Zhang, Tania F Gendron, Peter O Bauer, Jeannie Chew, Wang-Yong Yang, Erik Fostvedt, Karen Jansen-West, Veronique V Belzil, Pamela Desaro, Amelia Johnston, Karen Overstreet, Seok-Yoon Oh, Peter K Todd, James D Berry, Merit E Cudkowicz, Bradley F Boeve, Dennis Dickson, Mary Kay Floeter, Bryan J Traynor, Claudia Morelli, Antonia Ratti, Vincenzo Silani, Rosa Rademakers, Robert H Brown, Jeffrey D Rothstein, Kevin B Boylan, Leonard Petrucelli, Matthew D Disney.

Abstract

Year: 2014 PMID： 28898625 DOI： 10.1016/j.neuron.2014.09.019

Source DB: PubMed Journal: Neuron ISSN： 0896-6273 Impact factor: 17.173

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16 in total

1. A Toxic RNA Catalyzes the Cellular Synthesis of Its Own Inhibitor, Shunting It to Endogenous Decay Pathways.

Authors: Raphael I Benhamou; Alicia J Angelbello; Eric T Wang; Matthew D Disney
Journal: Cell Chem Biol Date: 2020-01-24 Impact factor: 8.116

2. Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.

Authors: Yingxiao Shi; Shaoyu Lin; Kim A Staats; Yichen Li; Wen-Hsuan Chang; Shu-Ting Hung; Eric Hendricks; Gabriel R Linares; Yaoming Wang; Esther Y Son; Xinmei Wen; Kassandra Kisler; Brent Wilkinson; Louise Menendez; Tohru Sugawara; Phillip Woolwine; Mickey Huang; Michael J Cowan; Brandon Ge; Nicole Koutsodendris; Kaitlin P Sandor; Jacob Komberg; Vamshidhar R Vangoor; Ketharini Senthilkumar; Valerie Hennes; Carina Seah; Amy R Nelson; Tze-Yuan Cheng; Shih-Jong J Lee; Paul R August; Jason A Chen; Nicholas Wisniewski; Victor Hanson-Smith; T Grant Belgard; Alice Zhang; Marcelo Coba; Chris Grunseich; Michael E Ward; Leonard H van den Berg; R Jeroen Pasterkamp; Davide Trotti; Berislav V Zlokovic; Justin K Ichida
Journal: Nat Med Date: 2018-02-05 Impact factor: 53.440

3. Arginine-rich dipeptide-repeat proteins as phase disruptors in C9-ALS/FTD.

Authors: Hana M Odeh; James Shorter
Journal: Emerg Top Life Sci Date: 2020-12-11

4. Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity.

Authors: Juan A Ortega; Elizabeth L Daley; Sukhleen Kour; Marisa Samani; Liana Tellez; Haley S Smith; Elizabeth A Hall; Y Taylan Esengul; Yung-Hsu Tsai; Tania F Gendron; Christopher J Donnelly; Teepu Siddique; Jeffrey N Savas; Udai B Pandey; Evangelos Kiskinis
Journal: Neuron Date: 2020-02-13 Impact factor: 17.173

Review 5. Disruption of RNA Metabolism in Neurological Diseases and Emerging Therapeutic Interventions.

Authors: Julia K Nussbacher; Ricardos Tabet; Gene W Yeo; Clotilde Lagier-Tourenne
Journal: Neuron Date: 2019-04-17 Impact factor: 17.173

Review 6. Targeting RNA in mammalian systems with small molecules.

Authors: Anita Donlic; Amanda E Hargrove
Journal: Wiley Interdiscip Rev RNA Date: 2018-05-03 Impact factor: 9.957

7. Approved Anti-cancer Drugs Target Oncogenic Non-coding RNAs.

Authors: Sai Pradeep Velagapudi; Matthew G Costales; Balayeshwanth R Vummidi; Yoshio Nakai; Alicia J Angelbello; Tuan Tran; Hafeez S Haniff; Yasumasa Matsumoto; Zi Fu Wang; Arnab K Chatterjee; Jessica L Childs-Disney; Matthew D Disney
Journal: Cell Chem Biol Date: 2018-06-28 Impact factor: 8.116