Gemita Manríquez P1, Carlos Escudero O2. 1. Hospital Clínico Herminda Martin, Chillán, Chile. 2. Laboratorio de Fisiología Vascular, Departamento de Ciencias Básicas, Universidad del Bío Bío, Chillán, Chile.
Abstract
AIM: To analyze socio-demographic as maternal and newborn factors associated with neonatal mortality in a tertiary hospital in Chile. PATIENTS AND METHOD: A retrospective analysis of case (neonatal death) and control (live births) was performed. A match 1:2 proportion considering year, month of birth and gender was made. By reviewing medical records and existing databases, we analyzed sociodemographic and pathophysiological variables of the mother and their newborn in a period between 2010 and 2014. RESULTS: During the period of study 81 neonatal deaths occurred in the hospital, with an estimated rate of 5.8 per thousand live births. Sixty-five cases were recruted, who were compared with 130 controls. The main causes of death were prematurity and congenital malformations. It was found that the presence of preterm birth (OR: 3; 95% CI 1.1-8.7), newborn small for gestational age (OR: 4; 95% CI 1.7-12.1) Apgar score at minute 4-7 (OR: 4; 95% CI 1.8-10.5), maternal activity outside the household (OR: 4; 95% CI 2.3-8.7), and cesarean delivery (OR: 3; 95% CI 1.5-5.6) were the most prevalent risk factors. CONCLUSION: Neonatal mortality is associated with prematurity. Therefore it is of relevance to continue promoting efforts to prevent preterm birth.
AIM: To analyze socio-demographic as maternal and newborn factors associated with neonatal mortality in a tertiary hospital in Chile. PATIENTS AND METHOD: A retrospective analysis of case (neonatal death) and control (live births) was performed. A match 1:2 proportion considering year, month of birth and gender was made. By reviewing medical records and existing databases, we analyzed sociodemographic and pathophysiological variables of the mother and their newborn in a period between 2010 and 2014. RESULTS: During the period of study 81 neonatal deaths occurred in the hospital, with an estimated rate of 5.8 per thousand live births. Sixty-five cases were recruted, who were compared with 130 controls. The main causes of death were prematurity and congenital malformations. It was found that the presence of preterm birth (OR: 3; 95% CI 1.1-8.7), newborn small for gestational age (OR: 4; 95% CI 1.7-12.1) Apgar score at minute 4-7 (OR: 4; 95% CI 1.8-10.5), maternal activity outside the household (OR: 4; 95% CI 2.3-8.7), and cesarean delivery (OR: 3; 95% CI 1.5-5.6) were the most prevalent risk factors. CONCLUSION: Neonatal mortality is associated with prematurity. Therefore it is of relevance to continue promoting efforts to prevent preterm birth.
Authors: Nayeri Reyes-Saavedra; Patricia C Castelán-Villagrana; Ivette Mata-Maqueda; Juan C Solís-Sáinz Journal: Saudi Med J Date: 2022-03 Impact factor: 1.422