Literature DB >> 28895955

Atopic dermatitis: pathogenesis.

Emma Guttman-Yassky1, Andrea Waldman2,3, Jusleen Ahluwalia2,3, Peck Y Ong4,5, Lawrence F Eichenfield2,3.   

Abstract

Atopic Dermatitis (AD) is a complex inflammatory cutaneous disorder characterized by immune mediated inflammation and epidermal barrier dysfunction. Arising from a complex interplay between environmental and genetic factors, the definitive etiology of AD is perplexing and controversial. Advances in molecular medicine are radically transforming our understanding of AD pathogenesis. Increasing knowledge on the pathogenesis of AD results in novel therapeutic targets and pathways. This article details the pathogenesis section of the Curriculum United for Better Eczema Care (CUBE-C), facilitating primary care and sub-specialist education on the scientific advances driving recent AD therapeutic innovations. ©2017 Frontline Medical Communications.

Entities:  

Mesh：

Year:  2017        PMID： 28895955     DOI： 10.12788/j.sder.2017.036

Source DB:  PubMed          Journal:  Semin Cutan Med Surg        ISSN： 1085-5629


  14 in total

1.  A comparative study on a biodegradable hyaluronic acid microneedle patch with a needleless patch for dry skin in atopic dermatitis: a single-blinded, split-body, randomized controlled trial.

Authors:  Ji-Hoon Song; Eun Jin An; Chang Yub Sung; Do Hyeon Jeong; Gihyun Lee; Soo-Yeon Park
Journal:  Arch Dermatol Res       Date:  2022-10-15       Impact factor: 3.033

Review 2.  Disease trajectories in childhood atopic dermatitis: an update and practitioner's guide.

Authors:  A D Irvine; P Mina-Osorio
Journal:  Br J Dermatol       Date:  2019-05-15       Impact factor: 9.302

Review 3.  The Efficacy and Safety of Abrocitinib as a Treatment Option for Atopic Dermatitis: A Short Report of the Clinical Data.

Authors:  Maddalena Napolitano; Gabriella Fabbrocini; Angelo Ruggiero; Vincenzo Marino; Mariateresa Nocerino; Cataldo Patruno
Journal:  Drug Des Devel Ther       Date:  2021-03-10       Impact factor: 4.162

Review 4.  Atopic Dermatitis as a Multifactorial Skin Disorder. Can the Analysis of Pathophysiological Targets Represent the Winning Therapeutic Strategy?

Authors:  Irene Magnifico; Giulio Petronio Petronio; Noemi Venditti; Marco Alfio Cutuli; Laura Pietrangelo; Franca Vergalito; Katia Mangano; Davide Zella; Roberto Di Marco
Journal:  Pharmaceuticals (Basel)       Date:  2020-11-22

Review 5.  Probiotics in the Management of Atopic Dermatitis for Children: A Case-Based Review.

Authors:  Ashila Putri Disamantiaji; Endang Farihatul Izza; Muhamad Faza Soelaeman; Tannia Sembiring; Melva Louisa
Journal:  Dermatol Res Pract       Date:  2020-12-07

6.  Peroxisomal Fatty Acid Oxidation and Glycolysis Are Triggered in Mouse Models of Lesional Atopic Dermatitis.

Authors:  Petra Pavel; Géraldine Leman; Martin Hermann; Christian Ploner; Thomas O Eichmann; Deborah Minzaghi; Franz P W Radner; Barbara Del Frari; Robert Gruber; Sandrine Dubrac
Journal:  JID Innov       Date:  2021-06-15

Review 7.  Role of AHR Ligands in Skin Homeostasis and Cutaneous Inflammation.

Authors:  Nieves Fernández-Gallego; Francisco Sánchez-Madrid; Danay Cibrian
Journal:  Cells       Date:  2021-11-15       Impact factor: 6.600

8.  The Anti-Inflammatory and Anti-Pruritus Mechanisms of Huanglian Jiedu Decoction in the Treatment of Atopic Dermatitis.

Authors:  Yubin Xu; Saizhen Chen; Lingling Zhang; Guirong Chen; Jinguang Chen
Journal:  Front Pharmacol       Date:  2021-12-02       Impact factor: 5.810

Review 9.  Immunological Aspects of Skin Aging in Atopic Dermatitis.

Authors:  Georgeta St Bocheva; Radomir M Slominski; Andrzej T Slominski
Journal:  Int J Mol Sci       Date:  2021-05-27       Impact factor: 5.923

Review 10.  JAK-STAT Inhibitors in Atopic Dermatitis from Pathogenesis to Clinical Trials Results.

Authors:  Krzysztof Szalus; Magdalena Trzeciak; Roman J Nowicki
Journal:  Microorganisms       Date:  2020-11-06
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