Literature DB >> 28893103

What's next for chronobiology and drug discovery.

Zheng Chen1.   

Abstract

Entities:  

Keywords:  Circadian clock; chronotherapy and chronomedicine; clock-modulating molecules; clock-related diseases and aging; human trials

Mesh:

Year:  2017        PMID: 28893103      PMCID: PMC6134399          DOI: 10.1080/17460441.2017.1378179

Source DB:  PubMed          Journal:  Expert Opin Drug Discov        ISSN: 1746-0441            Impact factor:   6.098


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  24 in total

Review 1.  Circadian time signatures of fitness and disease.

Authors:  Joseph Bass; Mitchell A Lazar
Journal:  Science       Date:  2016-11-25       Impact factor: 47.728

2.  A circadian gene expression atlas in mammals: implications for biology and medicine.

Authors:  Ray Zhang; Nicholas F Lahens; Heather I Ballance; Michael E Hughes; John B Hogenesch
Journal:  Proc Natl Acad Sci U S A       Date:  2014-10-27       Impact factor: 11.205

3.  Time-restricted feeding without reducing caloric intake prevents metabolic diseases in mice fed a high-fat diet.

Authors:  Megumi Hatori; Christopher Vollmers; Amir Zarrinpar; Luciano DiTacchio; Eric A Bushong; Shubhroz Gill; Mathias Leblanc; Amandine Chaix; Matthew Joens; James A J Fitzpatrick; Mark H Ellisman; Satchidananda Panda
Journal:  Cell Metab       Date:  2012-05-17       Impact factor: 27.287

4.  The nuclear receptor REV-ERBα mediates circadian regulation of innate immunity through selective regulation of inflammatory cytokines.

Authors:  Julie E Gibbs; John Blaikley; Stephen Beesley; Laura Matthews; Karen D Simpson; Susan H Boyce; Stuart N Farrow; Kathryn J Else; Dave Singh; David W Ray; Andrew S I Loudon
Journal:  Proc Natl Acad Sci U S A       Date:  2011-12-19       Impact factor: 11.205

5.  Identification and validation of cryptochrome inhibitors that modulate the molecular circadian clock.

Authors:  Sung Kook Chun; Jaebong Jang; Sooyoung Chung; Hwayoung Yun; Nam-Jung Kim; Jong-Wha Jung; Gi Hoon Son; Young-Ger Suh; Kyungjin Kim
Journal:  ACS Chem Biol       Date:  2014-01-03       Impact factor: 5.100

Review 6.  Pharmacological modulators of the circadian clock as potential therapeutic drugs: focus on genotoxic/anticancer therapy.

Authors:  Marina P Antoch; Roman V Kondratov
Journal:  Handb Exp Pharmacol       Date:  2013

7.  The Small Molecule Nobiletin Targets the Molecular Oscillator to Enhance Circadian Rhythms and Protect against Metabolic Syndrome.

Authors:  Baokun He; Kazunari Nohara; Noheon Park; Yong-Sung Park; Bobby Guillory; Zhaoyang Zhao; Jose M Garcia; Nobuya Koike; Cheng Chi Lee; Joseph S Takahashi; Seung-Hee Yoo; Zheng Chen
Journal:  Cell Metab       Date:  2016-04-12       Impact factor: 27.287

Review 8.  Transcriptional architecture of the mammalian circadian clock.

Authors:  Joseph S Takahashi
Journal:  Nat Rev Genet       Date:  2016-12-19       Impact factor: 53.242

Review 9.  Genetic basis of human circadian rhythm disorders.

Authors:  Christopher R Jones; Angela L Huang; Louis J Ptáček; Ying-Hui Fu
Journal:  Exp Neurol       Date:  2012-07-28       Impact factor: 5.330

Review 10.  Overcoming Chemical, Biological, and Computational Challenges in the Development of Inhibitors Targeting Protein-Protein Interactions.

Authors:  Luca Laraia; Grahame McKenzie; David R Spring; Ashok R Venkitaraman; David J Huggins
Journal:  Chem Biol       Date:  2015-06-18
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  3 in total

Review 1.  Emerging relevance of circadian rhythms in headaches and neuropathic pain.

Authors:  Mark J Burish; Zheng Chen; Seung-Hee Yoo
Journal:  Acta Physiol (Oxf)       Date:  2018-07-25       Impact factor: 6.311

Review 2.  Nobiletin: Targeting the Circadian Network to Promote Bioenergetics and Healthy Aging.

Authors:  E Mileykovskaya; S-H Yoo; W Dowhan; Z Chen
Journal:  Biochemistry (Mosc)       Date:  2020-12       Impact factor: 2.487

3.  Coordinate Regulation of Cholesterol and Bile Acid Metabolism by the Clock Modifier Nobiletin in Metabolically Challenged Old Mice.

Authors:  Kazunari Nohara; Travis Nemkov; Angelo D'Alessandro; Seung-Hee Yoo; Zheng Chen
Journal:  Int J Mol Sci       Date:  2019-09-01       Impact factor: 6.208

  3 in total

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