Literature DB >> 28893026

Superior Vena Cava as Gateway to Heart: Metastatic Breast Carcinoma Causing Ball in a Loop Metastasis to Right Atrium.

Harpreet Singh Sandhu1, Sampath Kumar Mahadevappa Mahendrakar2, Sulaiman Sadruddin Ladhani3, Azizullah Hafizullah Khan4, Yunus Shafi Loya5.   

Abstract

Breast carcinoma is the most common invasive cancer in women worldwide. It metastasizes commonly to bone, lungs, regional lymph nodes and brain. Cardiac metastasis of lung and breast cancers is a known but rare complication of advanced disease with tumour metastasising to pericardium via the locoregional lymphatic system. Here we present a case of 59-year-old female presenting with right upper limb oedema, facial puffiness and features of Superior Vena Cava (SVC) syndrome 15 years after mastectomy and adjuvant chemotherapy, radiotherapy for carcinoma of the right breast. Further evaluation revealed extensive thrombus invading the right internal jugular vein, subclavian vein, SVC with intraluminal extension into right atrium causing ball in a loop obstruction at tricuspid valve. Whole body Positron emission tomography scan confirmed the diagnosis of extensive metastatic disease and patient was managed on palliative therapy. Haematogenous spread and intraluminal growth of metastatic deposits from breast carcinoma 15 years ago is rare and clinical presentation as SVC obstruction has not been reported in our review of literature.

Entities:  

Keywords:  Cardiac metastasis; Right atrial mass; Superior vena cava syndrome

Year:  2017        PMID: 28893026      PMCID: PMC5579767          DOI: 10.7860/JCDR/2017/26388.10183

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  13 in total

Review 1.  Clinical practice. Superior vena cava syndrome with malignant causes.

Authors:  Lynn D Wilson; Frank C Detterbeck; Joachim Yahalom
Journal:  N Engl J Med       Date:  2007-05-03       Impact factor: 91.245

2.  Asymptomatic right atrial myxoma originating from the inferior vena cava and right atrium junction in a patient with breast ductal adenocarcinoma.

Authors:  Necla Ozer; Onur Sinan Deveci; Sercan Okutucu; Metin Demircin
Journal:  Turk Kardiyol Dern Ars       Date:  2009-10

3.  [Echocardiography in patients with malignant metastatic neoplasms of the heart and great vessels].

Authors:  M Ohnishi; H Niwayama; Y Miyazawa; N Kondo; H Imai; Y Nishimoto; N Morooka; S Watanabe; Y Masuda; Y Inagaki
Journal:  J Cardiol       Date:  1990       Impact factor: 3.159

Review 4.  Cardiac myxoma: imaging features in 83 patients.

Authors:  Mary L Grebenc; Melissa L Rosado-de-Christenson; Curtis E Green; Allen P Burke; Jeffrey R Galvin
Journal:  Radiographics       Date:  2002 May-Jun       Impact factor: 5.333

Review 5.  Incidence of unilateral arm lymphoedema after breast cancer: a systematic review and meta-analysis.

Authors:  Tracey DiSipio; Sheree Rye; Beth Newman; Sandi Hayes
Journal:  Lancet Oncol       Date:  2013-03-27       Impact factor: 41.316

6.  Breast Cancer Care in India: The Current Scenario and the Challenges for the Future.

Authors:  Gaurav Agarwal; Pooja Ramakant
Journal:  Breast Care (Basel)       Date:  2008-02-22       Impact factor: 2.860

7.  Detection of an asymptomatic right-ventricle cardiac metastasis from a small-cell lung cancer by F-18-FDG PET/CT.

Authors:  Maria Victoria Orcurto; Angelika Bischof Delaloye; Igor Letovanec; Martina Martins Favre; John O Prior
Journal:  J Thorac Oncol       Date:  2009-01       Impact factor: 15.609

8.  Effect of comprehensive breast care on breast cancer outcomes: a community hospital based study from Mumbai, India.

Authors:  Anita Gadgil; Nobhojit Roy; Rengaswamy Sankaranarayanan; Richard Muwonge; Catherine Sauvaget
Journal:  Asian Pac J Cancer Prev       Date:  2012

Review 9.  Effects of age on the detection and management of breast cancer.

Authors:  Andrew McGuire; James A L Brown; Carmel Malone; Ray McLaughlin; Michael J Kerin
Journal:  Cancers (Basel)       Date:  2015-05-22       Impact factor: 6.639

Review 10.  Symptomatic cardiac metastases of breast cancer 27 years after mastectomy: a case report with literature review--pathophysiology of molecular mechanisms and metastatic pathways, clinical aspects, diagnostic procedures and treatment modalities.

Authors:  Darko Katalinic; Ranka Stern-Padovan; Irena Ivanac; Ivan Aleric; Damir Tentor; Nora Nikolac; Fedor Santek; Antonio Juretic; Stjepko Plestina
Journal:  World J Surg Oncol       Date:  2013-01-23       Impact factor: 2.754

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  2 in total

1.  Rare report of concurrent metastasis on bilateral atrial myxoma masses.

Authors:  Sahar Ayati; Ahmad Amouzeshi; Amir Dehghani-Samani
Journal:  ARYA Atheroscler       Date:  2021-07

Review 2.  Rare sites of breast cancer metastasis: a review.

Authors:  Rosa Di Micco; Letizia Santurro; Maria Luisa Gasparri; Veronica Zuber; Enrico Fiacco; Guglielmo Gazzetta; Chanel Elisha Smart; Alice Valentini; Oreste Davide Gentilini
Journal:  Transl Cancer Res       Date:  2019-10       Impact factor: 1.241

  2 in total

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