Literature DB >> 28893025

Primary Squamous Cell Carcinoma of Submandibular Salivary Gland: A Case Report.

Manmohan Agarwal1, Lakshmi Agarwal2, Rajeev Saxena3.   

Abstract

Primary Squamous Cell Carcinoma (PSCC) of submandibular salivary gland is a rare occurrence. Careful clinical and histopathological examination is must to diagnose it. The treatment protocol of this rare disease is not clearly defined. Though surgery is primary treatment, role of adjuvant treatment is not clear. A 40-year-old male presented to us with asymptomatic upper neck swelling. Triple endoscopy, cross-sectional investigation and FNAC suggested primary squamous cell carcinoma of right submandibular salivary gland. He was treated with bilateral modified neck dissection and wide excision of sub mandibular gland with surrounding muscles. Post surgery, he had undergone interval chemotherapy followed by radiotherapy. The patient is still on regular follow up at an interval of three months without any evidence of disease recurrence. Though difficult to diagnose and treat this kind of rare variant of salivary neoplasms, awareness of the disease and aggressive treatment depending on histopathology report, can help patient to achieve health.

Entities:  

Keywords:  Extra Capsular Extension; Muco-epidermoid carcinoma; Salivary neoplasms

Year:  2017        PMID: 28893025      PMCID: PMC5583916          DOI: 10.7860/JCDR/2017/26356.10158

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  7 in total

1.  Primary squamous cell carcinoma of the parotid gland: the importance of correct histological diagnosis.

Authors:  M B Flynn; S Maguire; S Martinez; T Tesmer
Journal:  Ann Surg Oncol       Date:  1999-12       Impact factor: 5.344

2.  Management and outcome of patients with malignant salivary gland tumors.

Authors:  R Bryan Bell; Eric J Dierks; Louis Homer; Bryce E Potter
Journal:  J Oral Maxillofac Surg       Date:  2005-07       Impact factor: 1.895

Review 3.  Squamous carcinoma in a major salivary gland: a review of the diagnostic considerations.

Authors:  J B Taxy
Journal:  Arch Pathol Lab Med       Date:  2001-06       Impact factor: 5.534

4.  Current role of chemotherapy in exclusive and integrated treatment of malignant tumours of salivary glands.

Authors:  G Cortesina; M Airoldi; F Palonta
Journal:  Acta Otorhinolaryngol Ital       Date:  2005-06       Impact factor: 2.124

5.  Squamous cell carcinoma of submandibular salivary gland: A rare case report.

Authors:  Vardendra Manvikar; Surekha Ramulu; Shilpa T Ravishanker; Chitra Chakravarthy
Journal:  J Oral Maxillofac Pathol       Date:  2014-05

Review 6.  Salivary gland tumours.

Authors:  P M Speight; A W Barrett
Journal:  Oral Dis       Date:  2002-09       Impact factor: 3.511

Review 7.  Systemic therapy in the management of metastatic or advanced salivary gland cancers.

Authors:  Aymen Lagha; Nesrine Chraiet; Mouna Ayadi; Sarra Krimi; Bassem Allani; Hela Rifi; Henda Raies; Amel Mezlini
Journal:  Head Neck Oncol       Date:  2012-05-04
  7 in total
  1 in total

1.  A Rare Case of Primary Squamous Cell Carcinoma of the Submandibular Salivary Gland: Brief Overview of Diagnostic Ambiguity and Treatment Challenges.

Authors:  Pawan Hingnikar; Anendd Jadhav; Nitin D Bhola
Journal:  Cureus       Date:  2022-09-06
  1 in total

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