Literature DB >> 28892920

Solid Variant of Aneurysmal Bone Cyst Masquerading as Malignancy.

Ashok Singh1, Abdul Majeed2, Supriya Mallick3, Shah Alam Khan4, Asit Ranjan Mridha5.   

Abstract

Solid Variant of Aneurysmal Bone Cyst (SVABC) is an uncommon neoplasm seen in young patients. The lesion presents clinically as well as on radiology like a malignant bone tumour. The aggressive features in most of the cases lead to a wrong diagnosis. Radiologically, it is expansile osteolytic with cortical breach being seen in many of the cases. We report two cases of SVABC which were misdiagnosed as malignant bone tumours. Both cases were seen in long bones. Radiologically both lesions were expansile, osteolytic, solid cystic, with destruction of cortex and were diagnosed as osteosarcomas. Both the cases were referred to us for further management and were subsequently diagnosed as SVABC. Being extremely rare these tumours have a high chance of getting misdiagnosed and knowledge of this entity along with close correlation with clinical, radiological and histopathological findings plays a critical role in accurately diagnosing this condition. An accurate diagnosis is of utmost importance as this changes the treatment drastically avoiding mutilating surgeries and unnecessary chemo radiotherapy.

Entities:  

Keywords:  Long bones; Malignant; Osteoclastic giant cells; Osteosarcoma; Radiology

Year:  2017        PMID: 28892920      PMCID: PMC5583895          DOI: 10.7860/JCDR/2017/25950.10306

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  11 in total

1.  Solid variant of aneurysmal bone cyst of the heel: a case report.

Authors:  Joanna A Lekka; Theofani V Gavresea; Gabriela A Stanc-Giannakopoulos; Nikolaos S Demertzis
Journal:  J Med Case Rep       Date:  2011-04-12

2.  Solid variant of aneurysmal bone cyst of the rib presenting as a left intrathoracic mass without radiological bone destruction.

Authors:  Hasan Özkan Gezer; Pelin Oğuzkurt; Abdülkerim Temiz; Şenay Demir; Akgün Hiçsönmez
Journal:  Turk J Pediatr       Date:  2014 May-Jun       Impact factor: 0.552

3.  Solid variant of aneurysmal bone cyst.

Authors:  F Bertoni; P Bacchini; R Capanna; P Ruggieri; R Biagini; A Ferruzzi; G Bettelli; P Picci; M Campanacci
Journal:  Cancer       Date:  1993-02-01       Impact factor: 6.860

4.  Solid variant of aneurysmal bone cyst of the thoracic spine: a case report.

Authors:  George Al-Shamy; Katherine Relyea; Adekunle Adesina; William E Whitehead; Daniel J Curry; Thomas G Luerssen; Andrew Jea
Journal:  J Med Case Rep       Date:  2011-06-30

5.  USP6 and CDH11 oncogenes identify the neoplastic cell in primary aneurysmal bone cysts and are absent in so-called secondary aneurysmal bone cysts.

Authors:  Andre M Oliveira; Antonio R Perez-Atayde; Carrie Y Inwards; Fabiola Medeiros; Victoria Derr; Bae-Li Hsi; Mark C Gebhardt; Andrew E Rosenberg; Jonathan A Fletcher
Journal:  Am J Pathol       Date:  2004-11       Impact factor: 4.307

6.  TRE17/USP6 oncogene translocated in aneurysmal bone cyst induces matrix metalloproteinase production via activation of NF-kappaB.

Authors:  Y Ye; L M Pringle; A W Lau; D N Riquelme; H Wang; T Jiang; D Lev; A Welman; G A Blobel; A M Oliveira; M M Chou
Journal:  Oncogene       Date:  2010-04-26       Impact factor: 9.867

7.  An unusual intraosseous lesion with fibroblastic, osteoclastic, osteoblastic, aneurysmal and fibromyxoid elements. "Solid" variant of aneurysmal bone cyst.

Authors:  N G Sanerkin; M G Mott; J Roylance
Journal:  Cancer       Date:  1983-06-15       Impact factor: 6.860

8.  Solid variant of aneurysmal bone cysts in long tubular bones: giant cell reparative granuloma.

Authors:  Hakan Ilaslan; Murali Sundaram; K Krishnan Unni
Journal:  AJR Am J Roentgenol       Date:  2003-06       Impact factor: 3.959

9.  "Solid" variant of aneurysmal bone cyst (extragnathic giant cell reparative granuloma) in the axial skeleton and long bones. A study of its morphologic spectrum and distinction from allied giant cell lesions.

Authors:  Y Oda; M Tsuneyoshi; N Shinohara
Journal:  Cancer       Date:  1992-12-01       Impact factor: 6.860

10.  Solid variant of aneurysmal bone cyst in the tibia treated with simple curettage without bone graft: a case report.

Authors:  Rumi Takechi; Takashi Yanagawa; Tetsuya Shinozaki; Toshio Fukuda; Kenji Takagishi
Journal:  World J Surg Oncol       Date:  2012-02-20       Impact factor: 2.754

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  2 in total

1.  Challenges in the Diagnosis and Treatment of Aneurysmal Bone Cyst in Patients with Unusual Features.

Authors:  Ziyad M Mohaidat; Salah R Al-Gharaibeh; Osama N Aljararhih; Murad T Nusairat; Ali A Al-Omari
Journal:  Adv Orthop       Date:  2019-08-04

2.  Solid variant ABC of long tubular bones: A diagnostic conundrum for the radiologist.

Authors:  Adarsh Ghosh; Anuradha Singh; Richa Yadav; Shah A Khan; Venkatesan S Kumar; Shivanand Gamanagatti
Journal:  Indian J Radiol Imaging       Date:  2019-10-30
  2 in total

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