Literature DB >> 28892466

Malignant transformation of a tailgut cyst.

Gianrocco Manco, Giovanni Giliberti, Giovanni Rolando, Fabio Gelsomino, Elena Zunarelli, Aldo Rossi.   

Abstract

INTRODUCTION: Tailgut cyst are congenital cystic lesion arising from remnant of the embryological postnatal gut. Tailgut cyst are multinodular, uncapsulated and usually well-circumscribed. Presacral cysts are rare in adult and most of the lesions are benign. Malignant degeneration can occur, however is extremely rare. CASE REPORT: We present the case of a 74 years old woman with slow increase in size and malignant degeneration of a tailgut cyst. Five years before, during the follow up after mastectomy for cancer, she manifested rise of CA 19-9 tumor marker and a presacral cystic collection on thoraco-abdominal CT. She was followed with CT and MRI that showed that the cyst, with a solid component of the wall, was growing larger. After a five-year evolution, the cyst was resected. The histological examination on the solid component demonstrated intestinal adenocarcinoma.
CONCLUSION: MRI ant TC can play essential role in the preoperative detection and characterization for the differential diagnosis, treatment strategies and evaluate neoplastic degeneration. Due to the risk of malignancy surgical resection must be performed after the diagnosis. Surgical therapy is mandatory when the cyst grow larger and a solid component is present. KEY WORDS: Presacral cyst, Retrorectal tumors, Tailgut cyst.

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Year:  2017        PMID: 28892466

Source DB:  PubMed          Journal:  Ann Ital Chir        ISSN: 0003-469X            Impact factor:   0.766


  1 in total

1.  Tailgut cyst adenocarcinoma.

Authors:  Pedro Martins; Rita Canotilho; Mariana Peyroteo; Mariana Afonso; Augusto Moreira; Abreu de Sousa
Journal:  Autops Case Rep       Date:  2019-12-13
  1 in total

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