Literature DB >> 2889139

Complementary DNA for a human subgroup IV immunoglobulin lambda-chain.

N Yamasaki1, S Komori, T Watanabe.   

Abstract

We have cloned a cDNA (p3C4 lambda 5) encoding a human immunoglobulin lambda-chain of human-mouse heterohybridoma, H6-3C4, which produces a human monoclonal antibody against human sperm surface antigen. Amino acid sequence deduced from the nucleotide sequence of V lambda (V lambda 3C4) of cloned cDNA was closely related to that of SHV lambda protein, a member of subgroup IV. Southern blot analysis of human genomic DNAs by using V lambda 3C4 as a probe detected at least 8 cross-hybridizing members of subgroup V lambda IV. Restriction enzyme fragment polymorphism (RFLP) appeared to be present in normal individuals with V lambda 3C4 gene.

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Year:  1987        PMID： 2889139     DOI： 10.1016/0161-5890(87)90010-1

Source DB:  PubMed          Journal:  Mol Immunol        ISSN： 0161-5890            Impact factor:   4.407


  11 in total

1.  Nucleotide sequences and three-dimensional modelling of the VH and VL domains of two human monoclonal antibodies specific for the D antigen of the human Rh-blood-group system.

Authors:  N C Hughes-Jones; J M Bye; D Beale; J Coadwell
Journal:  Biochem J       Date:  1990-05-15       Impact factor: 3.857

2.  First genomic sequence of a human Ig variable lambda gene belonging to subgroup III.

Authors:  J P Frippiat; P Chuchana; F Bernard; L Buluwela; G Lefranc; M P Lefranc
Journal:  Nucleic Acids Res       Date:  1990-12-11       Impact factor: 16.971

3.  HindIII RFLP of the human immunoglobulin V lambda III subgroup genes.

Authors:  P Chuchana; A Blancher; G Lefranc; M P Lefranc
Journal:  Nucleic Acids Res       Date:  1990-10-25       Impact factor: 16.971

4.  Isolation and characterization of a novel human gene expressed specifically in the cells of hematopoietic lineage.

Authors:  D Kitamura; H Kaneko; Y Miyagoe; T Ariyasu; T Watanabe
Journal:  Nucleic Acids Res       Date:  1989-11-25       Impact factor: 16.971

Review 5.  Structural and functional properties of human lambda-light-chain variable-region subgroups.

Authors:  A Solomon; D T Weiss
Journal:  Clin Diagn Lab Immunol       Date:  1995-07

Review 6.  The CDR1 sequences of a major proportion of human germline Ig VH genes are inherently susceptible to amino acid replacement.

Authors:  B Chang; P Casali
Journal:  Immunol Today       Date:  1994-08

7.  Complete sequence of the genes encoding the VH and VL regions of low- and high-affinity monoclonal IgM and IgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient.

Authors:  N Harindranath; I S Goldfarb; H Ikematsu; S E Burastero; R L Wilder; A L Notkins; P Casali
Journal:  Int Immunol       Date:  1991-09       Impact factor: 4.823

8.  Characterization of a lymphoblastoid line deleted for lambda immunglobulin genes.

Authors:  C A Hough; B N White; J J Holden
Journal:  Immunogenetics       Date:  1995       Impact factor: 2.846

9.  Expansion of a B-lymphocyte clone producing IgM auto-antibodies encoded by a somatically mutated VHI gene in the spleen of an autoimmune patient.

Authors:  S Jahn; B Niemann; T Winkler; J R Kalden; R von Baehr
Journal:  Rheumatol Int       Date:  1994       Impact factor: 2.631

10.  Immunoglobulin light chain class multiplicity and alternative organizational forms in early vertebrate phylogeny.

Authors:  J P Rast; M K Anderson; T Ota; R T Litman; M Margittai; M J Shamblott; G W Litman
Journal:  Immunogenetics       Date:  1994       Impact factor: 2.846
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