Literature DB >> 28891172

Urolithiasis is prevalent and associated with reduced bone mineral density in β-thalassaemia major.

Phillip Wong1,2,3, Frances Milat1,2,3, Peter J Fuller1,2,3,4, Peter G Kerr5, James C G Doery3,6, Danielle H Oh7, Dana Jackson8, Matthew T Gillespie1,4, Donald K Bowden9, Sant-Rayn Pasricha9,10,11, Ken K Lau3,8.   

Abstract

Asymptomatic urolithiasis is common and of mixed composition in patients with β-thalassaemia major. Twenty-seven subjects were imaged using dual-energy computer tomography to determine the presence and composition of urolithiasis. The prevalence of urolithiasis was 59% and affected patients generally had multiple stones, often with more than one component: struvite (33%), calcium oxalate (31%) and cystine (22%). Hypercalciuria was present in 78% of subjects and calcium-containing urolithiasis was associated with reduced femoral neck Z scores.
© 2017 Royal Australasian College of Physicians.

Entities:  

Keywords:  computed tomography; kidney stone; osteoporosis; thalassaemia; urolithiasis

Mesh:

Year:  2017        PMID: 28891172     DOI: 10.1111/imj.13533

Source DB:  PubMed          Journal:  Intern Med J        ISSN: 1444-0903            Impact factor:   2.048


  2 in total

1.  Assessment of Subclinical Renal Glomerular and Tubular Dysfunction in Children with Beta Thalassemia Major.

Authors:  Asmaa A Mahmoud; Doaa M Elian; Nahla Ms Abd El Hady; Heba M Abdallah; Shimaa Abdelsattar; Fatma O Khalil; Sameh A Abd El Naby
Journal:  Children (Basel)       Date:  2021-02-03

2.  Beta-thalassaemia major: Prevalence, risk factors and clinical consequences of hypercalciuria.

Authors:  Ludovica Aliberti; Irene Gagliardi; Maria Rita Gamberini; Andrea Ziggiotto; Martina Verrienti; Aldo Carnevale; Marta Bondanelli; Maria Chiara Zatelli; Maria Rosaria Ambrosio
Journal:  Br J Haematol       Date:  2022-06-29       Impact factor: 8.615

  2 in total

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