Literature DB >> 28890177

Lignanamides with potent antihyperlipidemic activities from the root bark of Lycium chinense.

Hui Chen1, Yu-Jie Li2, Yan-Jun Sun3, Jian-Hong Gong3, Kun Du3, Yan-Li Zhang3, Cheng-Fu Su4, Qian-Qian Han2, Xiao-Ke Zheng3, Wei-Sheng Feng5.   

Abstract

Seven new lignanamides, lyciumamides D-J (1-4 and 9-11), together with nine known analogues (5-8 and 12-16), were isolated from the root bark of Lycium chinense. The structures of the isolated compounds were elucidated on the basis of NMR spectroscopic and HRESIMS data. All isolated compounds were evaluated for antihyperlipidemic activities in HepG2 cells. The primary structure-activity relationships were discussed.
Copyright © 2017 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Antihyperlipidemic activity; Lignanamides; Lycium chinense

Mesh：

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Year:  2017        PMID： 28890177     DOI： 10.1016/j.fitote.2017.09.004

Source DB:  PubMed          Journal:  Fitoterapia        ISSN： 0367-326X            Impact factor:   2.882


  5 in total

1.  Ojayeonjonghwan, an oriental medicine composed of five seeds, protects against vasomotor and neurological disorders in estrogen-deficient rats.

Authors:  Byoung-Seob Ko; Jin Ah Ryuk; Joo Tae Hwang; Ting Zhang; Xuangao Wu; Sunmin Park
Journal:  Exp Biol Med (Maywood)       Date:  2019-02-05

2.  Analysis of Phenolic Compounds in Commercial Cannabis sativa L. Inflorescences Using UHPLC-Q-Orbitrap HRMS.

Authors:  Luana Izzo; Luigi Castaldo; Alfonso Narváez; Giulia Graziani; Anna Gaspari; Yelko Rodríguez-Carrasco; Alberto Ritieni
Journal:  Molecules       Date:  2020-01-31       Impact factor: 4.411

3.  Discovery of Active Ingredients Targeted TREM2 by SPR Biosensor-UPLC/MS Recognition System, and Investigating the Mechanism of Anti-Neuroinflammatory Activity on the Lignin-Amides from Datura metel Seeds.

Authors:  Si-Yi Wang; Yan Liu; Xiao-Mao Li; Adnan Mohammed Algradi; Hai Jiang; Yan-Ping Sun; Wei Guan; Juan Pan; Hai-Xue Kuang; Bing-You Yang
Journal:  Molecules       Date:  2021-09-30       Impact factor: 4.411

4.  A New Lignanamide from the Root of Lycium yunnanense Kuang and Its Antioxidant Activity.

Authors:  Xin-Heng Zheng; Yuan-Peng Huang; Qiu-Ping Liang; Wei Xu; Ting Lan; Guang-Xiong Zhou
Journal:  Molecules       Date:  2018-03-27       Impact factor: 4.411

5.  Antihyperlipidemic and Antioxidant Effects of Averrhoa Carambola Extract in High-Fat Diet-Fed Rats.

Authors:  Saleem H Aladaileh; Sultan A M Saghir; Kisantini Murugesu; Amirin Sadikun; Ashfaq Ahmad; Gurjeet Kaur; Ayman M Mahmoud; Vikneswaran Murugaiyah
Journal:  Biomedicines       Date:  2019-09-16
  5 in total

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