| Literature DB >> 28889386 |
Carina Bernardo1,2, Lúcio Lara Santos3,4.
Abstract
Patient-derived xenograft (PDX ) tumors are models developed by direct transplant of human tumors into immune-compromised hosts such as nude mice. These models retain the histological and genetic characteristics of the primary tumor and are considered a valuable platform for translational cancer research. This chapter describes the methodology to establish and propagate bladder cancer PDX model.Entities:
Keywords: Animal models; Bladder cancer; Drug testing; In vivo; Tumorgraft; Xenograft
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Year: 2018 PMID： 28889386 DOI： 10.1007/978-1-4939-7234-0_14
Source DB: PubMed Journal: Methods Mol Biol ISSN： 1064-3745