Literature DB >> 28888322

TOR, the Gateway to Cellular Metabolism, Cell Growth, and Disease.

John Blenis1.   

Abstract

Michael N. Hall is this year's recipient of the Lasker Basic Medical Research Award for the identification of the target of rapamycin, TOR. TOR is a master regulator of the cell's growth and metabolic state, and its dysregulation contributes to a variety of diseases, including diabetes, obesity, neurodegenerative disorders, aging, and cancer, making the TOR pathway an attractive therapeutic target.
Copyright © 2017 The Author(s). Published by Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 28888322     DOI： 10.1016/j.cell.2017.08.019

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


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