Literature DB >> 28888302

A Systematic Review of the Effectiveness of Laser Therapy for Hypertrophic Burn Scars.

Jennifer Zuccaro1, Natalia Ziolkowski2, Joel Fish3.   

Abstract

The objective of this systematic review was to assess the effectiveness of laser therapy for the treatment of hypertrophic burn scars. Improvements in scar symptoms following laser treatment were reported in 11 of the 12 included studies. However, issues related to overall quality and risk of bias were present in all studies. As a result, there is insufficient scientific evidence to determine the effectiveness of laser therapy from this systematic review. Future studies that use more rigorous study designs such as randomized controlled trials are needed to support the use of laser therapy for hypertrophic burn scars.
Copyright © 2017 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Burn; Hypertrophic; Laser therapy; Scar; Scar management

Mesh:

Year:  2017        PMID: 28888302     DOI: 10.1016/j.cps.2017.05.008

Source DB:  PubMed          Journal:  Clin Plast Surg        ISSN: 0094-1298            Impact factor:   2.017


  8 in total

1.  Early Laser for Burn Scars (ELABS): protocol for a multi-centre randomised, controlled trial of both the effectiveness and cost-effectiveness of the treatment of hypertrophic burn scars with Pulsed Dye Laser and standard care compared to standard care alone [version 1; peer review: 2 approved].

Authors:  Mark Brewin; Sharon Docherty; Vanessa Heaslip; Katie Breheny; Jonathon Pleat; Shelley Rhodes; Paul P M van Zuijlen; Mamta Shah
Journal:  NIHR Open Res       Date:  2022-01-18

2.  Identification of crucial noncoding RNAs and mRNAs in hypertrophic scars via RNA sequencing.

Authors:  Xiaodong Li; Zeliang He; Julei Zhang; Yan Han
Journal:  FEBS Open Bio       Date:  2021-05-12       Impact factor: 2.693

3.  MicroRNA-26a inhibits hyperplastic scar formation by targeting Smad2.

Authors:  Jun Qi; Yifei Liu; Kesu Hu; Yi Zhang; Yangyang Wu; Xia Zhang
Journal:  Exp Ther Med       Date:  2018-03-21       Impact factor: 2.447

Review 4.  Advancements in Regenerative Strategies Through the Continuum of Burn Care.

Authors:  Randolph Stone Ii; Shanmugasundaram Natesan; Christine J Kowalczewski; Lauren H Mangum; Nicholas E Clay; Ryan M Clohessy; Anders H Carlsson; David H Tassin; Rodney K Chan; Julie A Rizzo; Robert J Christy
Journal:  Front Pharmacol       Date:  2018-07-09       Impact factor: 5.810

5.  Inhibition of sphingosine kinase 2 attenuates hypertrophic scar formation via upregulation of Smad7 in human hypertrophic scar fibroblasts.

Authors:  Jian Zeng; Bin Jiang; Xia Xiao; Rou Zhang
Journal:  Mol Med Rep       Date:  2020-07-09       Impact factor: 2.952

6.  tRNA‑derived small RNAs: A novel class of small RNAs in human hypertrophic scar fibroblasts.

Authors:  Yaping Zhang; Qin Deng; Longxiang Tu; Dan Lv; Dewu Liu
Journal:  Int J Mol Med       Date:  2019-11-25       Impact factor: 4.101

7.  Efficacy and safety of a dual-scan protocol for carbon dioxide laser in the treatment of split-thickness skin graft contraction in a red Duroc pig model.

Authors:  Jie Li; Sally Kiu-Huen Ng; Wenjing Xi; Zheng Zhang; Xiaodian Wang; Hua Li; Weijie Su; Jingyan Wang; Yixin Zhang
Journal:  Burns Trauma       Date:  2021-12-31

8.  MicroRNA‑486‑5p inhibits the growth of human hypertrophic scar fibroblasts by regulating Smad2 expression.

Authors:  Yingying Shi; Luping Wang; Pijun Yu; Yi Liu; Wei Chen
Journal:  Mol Med Rep       Date:  2019-04-24       Impact factor: 2.952

  8 in total

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