A Izquierdo-Dominguez1, I Jauregui2, A Del Cuvillo3, J Montoro4, I Davila5, J Sastre6, J Bartra7, M Ferrer8, I Alobid9, J Mullol10, A L Valero11. 1. Servicio de Alergologia, Consorci Sanitari de Terrassa and Clinica Diagonal, Barcelona, Spain. 2. Servicio de Alergologia, Hospital de Basurto, Bilbao, Spain. 3. Unidad de Rinitis y Asma, UGC ORL, Hospital de Jerez, Cadiz, Spain. 4. Unidad de Alergia, Hospital Universitario Arnau de Vilanova, Facultad de Medicina, Universidad Catolica de Valencia San Vicente Martir, Valencia, Spain. 5. Servicio de Inmuno-Alergia, Hospital Clinico, Salamanca, Spain. 6. Servicio de Alergia, Fundacion Jimenez Diaz, Madrid, Spain. 7. Servicio de Neumologia y Alergia, Hospital Clinic i Universitari, Institut d Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain. 8. Departamento de Alergia, Clinica Universitaria Navarra, Pamplona, Spain. 9. Unitat de Rinologia i Clinica de l Olfacte, Servei d Otorinolaringologia, Hospital Clinic, IDIBAPS, Centro de Investigacion Biomedica em Red en Enfermedades Respiratorias (CIBERES), Barcelona, Spain. 10. Institut d Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Unitat de Rinologia i Clinica de l Olfacte, Servei d Otorinolaringologia, Hospital Clinic, Universitat de Barcelona, Centro de Investigacion Biomedica en Red en Enfermedades Respiratorias. 11. Servicio de Neumologia y Alergia, Hospital Clinic i Universitari; Institut d Investigacions Biomediques August Pi i Sunyer (IDIBAPS); and CIBER de Enfermedades Respiratorias (CIBERES), Barcelona, Catalonia, Spain.
Abstract
BACKGROUND: Allergic rhinitis (AR) is a highly prevalent disease worldwide. Although a number of studies have described AR, no studies compared children and adult AR populations. The objective was to compare the AR characteristics between two AR cohorts of children and adults. METHODS: Two AR cohorts (children and adults) from Spain were studied through observational cross-sectional multicentre studies. AR was classified based on classical (allergen exposure), original (o-ARIA), and modified (m-ARIA) ARIA criteria. AR was evaluated by Total 4-Symptoms Score (T4SS), and disease severity by Visual Analogue Scale (VAS, 0-100 mm). AR comorbidities were also evaluated. RESULTS: A total of 5,405 patients (1,275 children, 4,130 adults) were studied. According to symptoms duration, intermittent AR was more frequent in children than in adults. Using o-ARIA severity, more children than adults had moderate/severe AR while, using m-ARIA, more children than adults had severe AR. T4SS was higher in adults than in children. Moreover, VAS was also higher in adults than in children. In addition, asthma atopic dermatitis and conjunctivitis were more associated to children than adults with AR, the frequency of this comorbidities increasing according to higher severity. CONCLUSIONS: AR in children was more intermittent, severe, with less symptoms but with more comorbidities than in adults. These results suggest AR has similarities but also significant differences between children and adults.
BACKGROUND: Allergic rhinitis (AR) is a highly prevalent disease worldwide. Although a number of studies have described AR, no studies compared children and adult AR populations. The objective was to compare the AR characteristics between two AR cohorts of children and adults. METHODS: Two AR cohorts (children and adults) from Spain were studied through observational cross-sectional multicentre studies. AR was classified based on classical (allergen exposure), original (o-ARIA), and modified (m-ARIA) ARIA criteria. AR was evaluated by Total 4-Symptoms Score (T4SS), and disease severity by Visual Analogue Scale (VAS, 0-100 mm). AR comorbidities were also evaluated. RESULTS: A total of 5,405 patients (1,275 children, 4,130 adults) were studied. According to symptoms duration, intermittent AR was more frequent in children than in adults. Using o-ARIA severity, more children than adults had moderate/severe AR while, using m-ARIA, more children than adults had severe AR. T4SS was higher in adults than in children. Moreover, VAS was also higher in adults than in children. In addition, asthma atopic dermatitis and conjunctivitis were more associated to children than adults with AR, the frequency of this comorbidities increasing according to higher severity. CONCLUSIONS: AR in children was more intermittent, severe, with less symptoms but with more comorbidities than in adults. These results suggest AR has similarities but also significant differences between children and adults.
Authors: Jewel Park; Joo Hee Park; Jaehyung Park; Jimi Choi; Tae Hoon Kim Journal: Int J Environ Res Public Health Date: 2020-08-05 Impact factor: 3.390