Literature DB >> 28887871

The hypothalamic regulation of metabolic adaptations to exercise.

T Fujikawa1,2, C M Castorena1, S Lee1, J K Elmquist1,3.   

Abstract

Our modern lifestyle is characterised by easy access to nutrient dense foods combined with limited physical activity. A sedentary lifestyle is one of several factors that have contributed to the global obesity epidemic and it also predisposes to chronic illnesses such as diabetes and cardiovascular disease. Although many studies have focused on the benefits of exercise in peripheral tissues, the contributions of the central nervous system to these exercise-induced metabolic adaptations are relatively unknown. The present review highlights the role of the ventromedial hypothalamus in regulating the metabolic response to exercise.
© 2017 British Society for Neuroendocrinology.

Entities:  

Keywords:  energy expenditure; exercise; hypothalamus; metabolism; ventromedial hypothalamus

Mesh：

Year:  2017        PMID： 28887871      PMCID： PMC6264914          DOI： 10.1111/jne.12533

Source DB:  PubMed          Journal:  J Neuroendocrinol        ISSN： 0953-8194            Impact factor:   3.627


  65 in total

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Review 5.  Neural control of energy balance: translating circuits to therapies.

Authors:  Laurent Gautron; Joel K Elmquist; Kevin W Williams
Journal:  Cell       Date:  2015-03-26       Impact factor: 41.582

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Journal:  Neuroscience       Date:  2011-05-31       Impact factor: 3.590

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Journal:  Annu Rev Physiol       Date:  1983       Impact factor: 19.318

Review 8.  SF-1 in the ventral medial hypothalamic nucleus: a key regulator of homeostasis.

Authors:  Ki Woo Kim; Jong-Woo Sohn; Daisuke Kohno; Yong Xu; Kevin Williams; Joel K Elmquist
Journal:  Mol Cell Endocrinol       Date:  2010-11-24       Impact factor: 4.102

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Journal:  Diabetes       Date:  1995-02       Impact factor: 9.461

Review 10.  Comparative effectiveness of exercise and drug interventions on mortality outcomes: metaepidemiological study.

Authors:  Huseyin Naci; John P A Ioannidis
Journal:  BMJ       Date:  2013-10-01
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  5 in total

Review 1.  Ventromedial hypothalamus glucose-inhibited neurones: A role in glucose and energy homeostasis?

Authors:  Pamela R Hirschberg; Pallabi Sarkar; Suraj B Teegala; Vanessa H Routh
Journal:  J Neuroendocrinol       Date:  2019-08-04       Impact factor: 3.627

Review 2.  Effects of metabolic state on the regulation of melanocortin circuits.

Authors:  Linh Lieu; Dominic Chau; Sadia Afrin; Yanbin Dong; Amber L Alhadeff; J Nicholas Betley; Kevin W Williams
Journal:  Physiol Behav       Date:  2020-06-28

3.  Hypothalamus-Muscle Parallel Induction of Metabolic Pathways Following Physical Exercise.

Authors:  Almog Katz; Meital Gonen; Yael Shahar; Asael Roichman; Batia Lerrer; Haim Yosef Cohen
Journal:  Front Neurosci       Date:  2022-07-19       Impact factor: 5.152

4.  CB1Rs in VMH neurons regulate glucose homeostasis but not body weight.

Authors:  Carlos M Castorena; Alexandre Caron; Natalie J Michael; Newaz I Ahmed; Amanda G Arnold; Jiwon Lee; Charlotte Lee; Chelsea Limboy; Arely Salazar Tinajero; Madison Granier; Simeng Wang; Jay D Horton; William L Holland; Syann Lee; Chen Liu; Teppei Fujikawa; Joel K Elmquist
Journal:  Am J Physiol Endocrinol Metab       Date:  2021-06-07       Impact factor: 5.900

5.  Ghrelin mediates exercise endurance and the feeding response post-exercise.

Authors:  Bharath K Mani; Carlos M Castorena; Sherri Osborne-Lawrence; Prasanna Vijayaraghavan; Nathan P Metzger; Joel K Elmquist; Jeffrey M Zigman
Journal:  Mol Metab       Date:  2018-01-31       Impact factor: 7.422
  5 in total

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