Literature DB >> 28886388

SnapShot: Connexins and Disease.

Dale W Laird1, Christian C Naus2, Paul D Lampe3.   

Abstract

The connexin family of membrane proteins enable gap junction formation and homeostasis, supporting communication between adjacent cells. This SnapShot highlights mutations in different connexins associated with human pathologies and how they affect gap junction function.
Copyright © 2017 Elsevier Inc. All rights reserved.

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Year:  2017        PMID： 28886388     DOI： 10.1016/j.cell.2017.08.034

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  17 in total

1.  A potent antagonist antibody targeting connexin hemichannels alleviates Clouston syndrome symptoms in mutant mice.

Authors:  Yuanyuan Kuang; Veronica Zorzi; Damiano Buratto; Gaia Ziraldo; Flavia Mazzarda; Chiara Peres; Chiara Nardin; Anna Maria Salvatore; Francesco Chiani; Ferdinando Scavizzi; Marcello Raspa; Min Qiang; Youjun Chu; Xiaojie Shi; Yu Li; Lili Liu; Yaru Shi; Francesco Zonta; Guang Yang; Richard A Lerner; Fabio Mammano
Journal:  EBioMedicine       Date:  2020-06-15       Impact factor: 8.143

Review 2.  Therapeutic strategies targeting connexins.

Authors:  Dale W Laird; Paul D Lampe
Journal:  Nat Rev Drug Discov       Date:  2018-10-12       Impact factor: 84.694

3.  Amyloid-β regulates gap junction protein connexin 43 trafficking in cultured primary astrocytes.

Authors:  Mahua Maulik; Lakshmy Vasan; Abhishek Bose; Saikat Dutta Chowdhury; Neelanjana Sengupta; Jayasri Das Sarma
Journal:  J Biol Chem       Date:  2020-08-31       Impact factor: 5.157

4.  Endothelial Pannexin 1 Channels Control Inflammation by Regulating Intracellular Calcium.

Authors:  Yang Yang; Leon J Delalio; Angela K Best; Edgar Macal; Jenna Milstein; Iona Donnelly; Ashley M Miller; Martin McBride; Xiaohong Shu; Michael Koval; Brant E Isakson; Scott R Johnstone
Journal:  J Immunol       Date:  2020-04-20       Impact factor: 5.422

Review 5.  Cellular mechanisms of connexin-based inherited diseases.

Authors:  Dale W Laird; Paul D Lampe
Journal:  Trends Cell Biol       Date:  2021-08-21       Impact factor: 20.808

6.  GJB4 and GJC3 variants in non-syndromic hearing impairment in Ghana.

Authors:  Samuel M Adadey; Kevin K Esoh; Osbourne Quaye; Geoffrey K Amedofu; Gordon A Awandare; Ambroise Wonkam
Journal:  Exp Biol Med (Maywood)       Date:  2020-06-11

7.  Tumor-suppressor microRNA-139-5p restrains bladder cancer cell line ECV-304 properties via targeting Connexin 43.

Authors:  Qiang Chi; Zhi-Yong Wang; Hong-Yang Li; Dian-Bin Song; Hui Xu; Guang Ma; Ze-Min Wang; Xiu-Ming Li
Journal:  Chin Med J (Engl)       Date:  2019-10-05       Impact factor: 2.628

Review 8.  Connexin Communication Compartments and Wound Repair in Epithelial Tissue.

Authors:  Marc Chanson; Masakatsu Watanabe; Erin M O'Shaughnessy; Alice Zoso; Patricia E Martin
Journal:  Int J Mol Sci       Date:  2018-05-03       Impact factor: 5.923

9.  Cisplatin-induced ototoxicity in organotypic cochlear cultures occurs independent of gap junctional intercellular communication.

Authors:  Julia Abitbol; Rianne Beach; Kevin Barr; Jessica Esseltine; Brian Allman; Dale Laird
Journal:  Cell Death Dis       Date:  2020-05-11       Impact factor: 8.469

10.  Cryo-EM structure of human Cx31.3/GJC3 connexin hemichannel.

Authors:  Hyuk-Joon Lee; Hyeongseop Jeong; Jaekyung Hyun; Bumhan Ryu; Kunwoong Park; Hyun-Ho Lim; Jejoong Yoo; Jae-Sung Woo
Journal:  Sci Adv       Date:  2020-08-28       Impact factor: 14.136
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